Allogeneic haematological stem cell transplantation (HSCT) has developed into
immunotherapy. Donor CD4+, CD8+ and natural killer (NK) cells have been reported to …

Relapse is a major cause of treatment failure after allogeneic hematopoietic stem cell
transplantation (alloHSCT). Treatment options for relapse have been inadequate, and the …

We have developed a real-time quantitative polymerase chain reaction (PCR) assay using
TaqMan technology (Applied Biosystems, Foster City, CA) for monitoring donor cell …

Purpose We recently reported that children with acute leukemias who show increasing
mixed chimerism (MC) after allogeneic stem-cell transplantation have a significantly …

Monitoring of Minimal Residual Disease After Allogeneic Stem-Cell Transplantation in
Relapsed Childhood Acute Lymphoblastic Leuk Page 1 Monitoring of Minimal Residual …

This study was performed to assess the utility of tumor-derived fragmentary DNA, or
circulating tumor DNA (ctDNA), for identifying high-risk patients for relapse of acute myeloid …

Sequential analysis of chimerism after allogeneic blood stem cell transplantation (BSCT)
has been shown to be predictive for graft failure and relapse. We have explored the impact …

We have retrospectively investigated the relationship between the level of minimal residual
disease (MRD) detected in bone marrow taken prior to conditioning therapy and outcome …

Allogeneic hematopoietic stem cell transplantation is an effective therapy for high-risk
leukemias. In children, graft manipulation based on the selective removal of αβT cells and B …

Introduction: Allogeneic hematopoietic stem cell transplantation (SCT) is the treatment of
choice for many malignant hematological disorders. Following recent improvements in non …