BACKGROUND Preimplantation genetic testing (PGT) encompasses methods that allow
embryos to be tested for severe inherited conditions or for chromosome abnormalities …

BACKGROUND Trophectoderm (TE) biopsy and next generation sequencing (NGS) are
currently the preferred techniques for preimplantation genetic testing for aneuploidies (PGT …

There is a high incidence of chromosomal abnormalities in early human embryos, whether
they are generated by natural conception or by assisted reproductive technologies (ART) …

STUDY QUESTION To what extent does a trophectoderm (TE) biopsy reliably reflect the
chromosomal constitution of the inner cell mass (ICM) in human blastocysts? SUMMARY …

Shallow whole-genome sequencing to infer copy number alterations (CNAs) in the human
genome is rapidly becoming the method par excellence for routine diagnostic use …

STUDY QUESTION We wanted to probe the opinions and current practices on
preimplantation genetic screening (PGS), and more specifically on PGS in its newest form …

STUDY QUESTION What is the accuracy of preimplantation genetic testing for aneuploidies
(PGT-A) when considering human peri-implantation outcomes in vitro? STUDY ANSWER …

Successful whole genome amplification (WGA) is a cornerstone of contemporary
preimplantation genetic testing (PGT). Choosing the most suitable WGA technique for PGT …

We report a sensitive PCR-based assay called Repetitive Element AneupLoidy Sequencing
System (RealSeqS) that can detect aneuploidy in samples containing as little as 3 pg of …

Objective To study the feasibility of in vitro maturation of ovarian tissue oocytes for fertility
preservation in transgender men on testosterone treatment. Design Cross-sectional study …