Lowering carbohydrate consumption effectively lowers glucose, but impacts on inflammation
are unclear. The objectives of this study were to: 1) determine whether reducing …

Fatty acids derived from adipose tissue lipolysis, intramyocellular triacylglycerol lipolysis, or
de novo lipogenesis serve a variety of functions in skeletal muscle. The two major fates of …

Adipose tissue is a dynamic endocrine organ, secreting a plethora of adipokines which play
a key role in regulating metabolic homeostasis and other physiological processes. An …

Toll-like receptor 4 (TLR4), a protein integral to innate immunity, is elevated in skeletal
muscle of obese and type 2 diabetic humans and has been implicated in the development of …

Objective Obesity and its consequences are among the biggest challenges facing the
healthcare system. Uterine leiomyomas are the most common gynecologic tumors. The risk …

The innate immune system contains multiple classes of pattern recognition receptors
(PRRs), which recognize pathogen‐associated molecular patterns (PAMPs) and danger …

摘要背景最近的研究表明果蝇样受体4 (Toll‐like receptor 4, TLR4) 通路介导了饱和游离脂肪酸
诱导的炎症反应. 白细胞介素8 (Interleukin‐8, IL‐8) 是一种促炎症因子, 能诱导体外培养的血管 …

Signal transducer and activator of transcription 3 (STAT3) is involved in cytokine-and
nutrient-induced insulin resistance. The role of STAT3 in the development of skeletal muscle …

Toll-like receptors (TLRs) are a class of receptors of the innate immune system which detect
pathogen-associated and danger-associated molecular patterns in order to initiate an …

Tissue inflammation is a tightly regulated process that normally serves to recruit the immune
system to sites of infection and injury and to facilitate tissue repair processes. When an …