The role of m6A methylation in therapy resistance in cancer
H Zhuang, B Yu, D Tao, X Xu, Y Xu, J Wang, Y Jiao… - Molecular cancer, 2023 - Springer
Cancer therapy resistance is the main cause of cancer treatment failure. The mechanism of
therapy resistance is a hot topic in epigenetics. As one of the most common RNA …
therapy resistance is a hot topic in epigenetics. As one of the most common RNA …
m6A methylation: a process reshaping the tumour immune microenvironment and regulating immune evasion
X Cao, Q Geng, D Fan, Q Wang, X Wang, M Zhang… - Molecular cancer, 2023 - Springer
Abstract N6-methyladenosine (m6A) methylation is the most universal internal modification
in eukaryotic mRNA. With elaborate functions executed by m6A writers, erasers, and …
in eukaryotic mRNA. With elaborate functions executed by m6A writers, erasers, and …
Role of main RNA modifications in cancer: N6-methyladenosine, 5-methylcytosine, and pseudouridine
C Xue, Q Chu, Q Zheng, S Jiang, Z Bao, Y Su… - Signal transduction and …, 2022 - nature.com
Cancer is one of the major diseases threatening human life and health worldwide.
Epigenetic modification refers to heritable changes in the genetic material without any …
Epigenetic modification refers to heritable changes in the genetic material without any …
Insight into the structure, physiological function, and role in cancer of m6A readers—YTH domain-containing proteins
J Liao, Y Wei, J Liang, J Wen, X Chen, B Zhang… - Cell death …, 2022 - nature.com
Abstract YT521-B homology (YTH) domain-containing proteins (YTHDF1-3, YTHDC1-2) are
the most crucial part of N6-methyladenosine (m6A) readers and play a regulatory role in …
the most crucial part of N6-methyladenosine (m6A) readers and play a regulatory role in …
m6A-immune-related lncRNA prognostic signature for predicting immune landscape and prognosis of bladder cancer
ZH Feng, YP Liang, JJ Cen, HH Yao, HS Lin… - Journal of Translational …, 2022 - Springer
Abstract Background N6-methyladenosine (m6A) related long noncoding RNAs (lncRNAs)
may have prognostic value in bladder cancer for their key role in tumorigenesis and innate …
may have prognostic value in bladder cancer for their key role in tumorigenesis and innate …
An m6A/m5C/m1A/m7G-related long non-coding RNA signature to predict prognosis and immune features of glioma
D Shao, Y Li, J Wu, B Zhang, S Xie, X Zheng… - Frontiers in …, 2022 - frontiersin.org
Background: Gliomas are the most common and fatal malignant type of tumor of the central
nervous system. RNA post-transcriptional modifications, as a frontier and hotspot in the field …
nervous system. RNA post-transcriptional modifications, as a frontier and hotspot in the field …
FGFR families: biological functions and therapeutic interventions in tumors
Q Liu, J Huang, W Yan, Z Liu, S Liu, W Fang - MedComm, 2023 - Wiley Online Library
There are five fibroblast growth factor receptors (FGFRs), namely, FGFR1–FGFR5. When
FGFR binds to its ligand, namely, fibroblast growth factor (FGF), it dimerizes and …
FGFR binds to its ligand, namely, fibroblast growth factor (FGF), it dimerizes and …
RNA m6A methylation in cancer
Z Wang, J Zhou, H Zhang, L Ge, J Li… - Molecular …, 2023 - Wiley Online Library
N 6‐methyladenosine (m6A) is one of the most abundant internal modifications in eukaryotic
messenger RNAs (mRNAs) and non‐coding RNAs (ncRNAs). It is a reversible and dynamic …
messenger RNAs (mRNAs) and non‐coding RNAs (ncRNAs). It is a reversible and dynamic …
Novel insights into mutual regulation between N6-methyladenosine modification and LncRNAs in tumors
N Zhang, Y Sun, Z Mei, Z He, S Gu - Cancer Cell International, 2023 - Springer
Abstract N6-methyladenosine (m6A), one of the most common RNA methylation
modifications, has emerged in recent years as a new layer of the regulatory mechanism …
modifications, has emerged in recent years as a new layer of the regulatory mechanism …
METTL3/m6A/IFIT2 regulates proliferation, invasion and immunity in esophageal squamous cell carcinoma
F Ge, Z Li, J Hu, Y Pu, F Zhao, L Kong - Frontiers in pharmacology, 2022 - frontiersin.org
Epigenetic regulation plays a critical role in the development, progression, and treatment of
tumors. The most common chemical modification of mRNA, called m6A, is essential for …
tumors. The most common chemical modification of mRNA, called m6A, is essential for …