During the past recent years, various therapies emerged in the era of breast cancer. Breast
cancer is a heterogeneous disease in which genetic and environmental factors are involved …

Breast cancer (BC) is a common cancer all over the world that affects women. BC is one of
the leading causes of cancer mortality in women, which today has decreased with the …

Newer treatment strategy based on proliferative nuclear marker Ki-67 targeted therapy holds
promise for prioritized/personalized treatment options with regard to improved survival and …

Following a diagnosis of breast cancer, the most immediate challenges in patient
management are the determination of prognosis and identification of the most appropriate …

Biomarkers play an essential role in the management of patients with invasive breast
cancer. For selecting patients likely to respond to endocrine therapy, both oestrogen …

Chemotherapy has historically been the mainstay of cancer treatment, but our
understanding of what drives a successful therapeutic response remains limited. The …

Systemic therapies for operable breast cancer patients have improved outcomes and have
thus become standard treatments. Recently, new molecular target drugs and regimens are …

Objective: Ki-67 plays an important function in cell division, but its exact role is still unknown.
Moreover, few works regarding its overall function were published. The present study …

Importance There is a clear need for a molecular subtyping approach in prostate cancer to
identify clinically distinct subgroups that benefit from specific therapies. Objectives To …

Although immunohistochemical detection of the Ki67 antigen has been used for many years
to assess cancer proliferation, this marker is still not recommended for routine use in clinical …