Repurposing of tibolone in Alzheimer's disease

GE Barreto - Biomolecules, 2023 - mdpi.com
Alzheimer's disease (AD) is a debilitating neurodegenerative disease characterised by the
accumulation of amyloid-beta and tau in the brain, leading to the progressive loss of memory …

Artificial intelligence for dementia prevention

D Newby, V Orgeta, CR Marshall… - Alzheimer's & …, 2023 - Wiley Online Library
INTRODUCTION A wide range of modifiable risk factors for dementia have been identified.
Considerable debate remains about these risk factors, possible interactions between them …

Potentially modifiable dementia risk factors in all Australians and within population groups: an analysis using cross-sectional survey data

RS See, F Thompson, S Russell, R Quigley… - The Lancet Public …, 2023 - thelancet.com
Background Dementia is the second leading cause of disease burden in Australia. We
aimed to calculate the population attributable fractions (PAFs) of dementia attributable to 11 …

Phosphodiesterase type 5 inhibitors in men with erectile dysfunction and the risk of alzheimer disease: a cohort study

M Adesuyan, YH Jani, D Alsugeir, R Howard, C Ju… - Neurology, 2024 - AAN Enterprises
Background and Objectives Repurposing phosphodiesterase type 5 inhibitors (PDE5Is) as
drugs for Alzheimer disease (AD) risk reduction has shown promise based on animal …

Changes in prevalence and incidence of dementia and risk factors for dementia: an analysis from cohort studies

N Mukadam, FJ Wolters, S Walsh, L Wallace… - The Lancet Public …, 2024 - thelancet.com
Background Some cohort studies have reported a decline in dementia prevalence and
incidence over time, although these findings have not been consistent across studies. We …

South Asian, Black and White ethnicity and the effect of potentially modifiable risk factors for dementia: A study in English electronic health records

N Mukadam, L Marston, G Lewis, R Mathur, E Lowther… - Plos one, 2023 - journals.plos.org
Introduction We aimed to investigate ethnic differences in the associations of potentially
modifiable risk factors with dementia. Methods We used anonymised data from English …

[HTML][HTML] Key Considerations When Developing and Implementing Digital Technology for Early Detection of Dementia-Causing Diseases Among Health Care …

S Wilson, C Tolley, R Mc Ardle, E Beswick… - Journal of Medical …, 2023 - jmir.org
Background The World Health Organization (WHO) promotes using digital technologies to
accelerate global attainment of health and well-being. This has led to a growth in research …

Estimating the prevalence of diagnosed Alzheimer disease in England across deprivation groups using electronic health records: a clinical practice research datalink …

TP Leahy, A Simpson, C Sammon, C Ballard… - BMJ open, 2023 - bmjopen.bmj.com
Objective Estimate the prevalence of diagnosed Alzheimer's disease (AD) and early
Alzheimer's disease (eAD) overall and stratified by age, sex and deprivation and …

Has COVID19 affected dementia diagnosis rates in England?

J Hazan, KY Liu, JD Isaacs, A Burns… - International Journal of …, 2023 - Wiley Online Library
Background The COVID19 pandemic impacted on the provision of care and routine activity
of all National Health Service (NHS) services. While General Practitioner referrals to memory …

A 3-UK-nation survey on dementia and the cost of living crisis: contributions of gender and ethnicity on struggling to pay for social care

C Giebel, B Heath - Aging & Mental Health, 2023 - Taylor & Francis
Objectives The aim of this 3-UK-nation online survey was to explore the impact of the cost of
living crisis on the lives of people with dementia and their carers, specifically on their ability …