Cardiovascular diseases (CVDs), such as ischaemic heart disease, cardiomyopathy,
atherosclerosis, hypertension, stroke and heart failure, are among the leading causes of …

Bipolar disorder is a heritable mental illness with complex etiology. We performed a genome-
wide association study of 41,917 bipolar disorder cases and 371,549 controls of European …

Gout is the most common inflammatory arthritis and occurs when hyperuricaemia, sustained
elevation of serum urate levels resulting in supersaturation of body tissues with urate, leads …

Background Apical periodontitis (AP) frequently presents as a chronic asymptomatic
disease. To arrive at a true diagnosis, in addition to the clinical examination, it is mandatory …

Depression is one of the most common comorbidities of many chronic medical diseases
including cancer and cardiovascular, metabolic, inflammatory and neurological disorders …

Background. Periodontal disease is a public health problem and is strongly associated with
systemic diseases; however, its worldwide distribution is not fully understood. Objective. To …

Objective To assess the prevalence of diabetes and its risk factors. Design Population
based, cross sectional study. Setting 31 provinces in mainland China with nationally …

Circadian rhythms are internal manifestations of the solar day that permit adaptations to
predictable environmental temporal changes. These~ 24-h rhythms are controlled by …

Musculoskeletal pain is a challenging condition for both patients and physicians. Many
adults have experienced one or more episodes of musculoskeletal pain at some time of their …

Background The burden of inflammatory bowel disease (IBD) is rising globally, with
substantial variation in levels and trends of disease in different countries and regions …