The prevalence of obesity, measured by body mass index, has risen to unacceptable levels
in both men and women in the United States and worldwide with resultant hazardous health …

Data on incidence, prevalence and burden of ADHD are crucial for clinicians, patients, and
stakeholders. We present the incidence, prevalence, and burden of ADHD globally and …

Summary Background The Global Burden of Diseases, Injuries, and Risk Factors Study
(GBD) 2017 comparative risk assessment (CRA) is a comprehensive approach to risk factor …

Background Alcohol and drug use can have negative consequences on the health,
economy, productivity, and social aspects of communities. We aimed to use data from the …

Background Neurological disorders are increasingly recognised as major causes of death
and disability worldwide. The aim of this analysis from the Global Burden of Diseases …

Osteoarthritis (OA) is an age-related metabolic disease. Low-grade inflammation and
oxidative stress are the last common pathway of OA. α-ketoglutarate (α-KG) is an essential …

Importance Approximately 5% of all primary care visits in adults are related to knee pain.
Osteoarthritis (OA), patellofemoral pain, and meniscal tears are among the most common …

Importance Rotavirus infection is the global leading cause of diarrhea-associated morbidity
and mortality among children younger than 5 years. Objectives To examine the extent of …

Background Rheumatic heart disease remains an important preventable cause of
cardiovascular death and disability, particularly in low-income and middle-income countries …

Background The lifetime risk of stroke has been calculated in a limited number of selected
populations. We sought to estimate the lifetime risk of stroke at the regional, country, and …