Although asthma is very common, affecting 5–10% of the population, the diagnosis of
asthma in adults remains a challenge in the real world, which results in both over-and under …

Microbial colonization on material surfaces is ubiquitous. Biofilms derived from surface‐
colonized microbes pose serious problems to the society from both an economical …

Iron is biologically essential, but also potentially toxic; as such it is tightly controlled at cell
and systemic levels to prevent both deficiency and overload. Iron regulatory proteins post …

Treatments for depression have improved, and their availability has markedly increased
since the 1980s. Mysteriously the general population prevalence of depression has not …

Opioid use disorder (OUD) is a chronic relapsing disorder that, whilst initially driven by
activation of brain reward neurocircuits, increasingly engages anti-reward neurocircuits that …

Non-communicable diseases (NCDs) are fatal for more than 38 million people each year
and are thus the main contributors to the global burden of disease accounting for 70% of …

Background Stroke is a leading cause of mortality and disability worldwide and the
economic costs of treatment and post-stroke care are substantial. The Global Burden of …

This review of trends in worldwide asthma prevalence starts with defining how asthma
prevalence is measured in populations and how it is analysed. Four population studies of …

Parkinson's disease (PD) is the second most common neurodegenerative disease
worldwide, and its treatment remains a big challenge. The pathogenesis of PD may be …

The effects of psychotherapies for depression have been examined in several hundreds of
randomized trials, but no recent network meta‐analysis (NMA) has integrated the results of …