Serum biomarkers for inflammatory bowel disease

P Chen, G Zhou, J Lin, L Li, Z Zeng, M Chen… - Frontiers in …, 2020 - frontiersin.org
Background: Inflammatory bowel disease (IBD), including Crohn's disease and ulcerative
colitis, is a chronic, inflammatory disorder of the gastrointestinal tract. As the novel …

Metabolomic analysis in inflammatory bowel disease: a systematic review

K Gallagher, A Catesson, JL Griffin… - Journal of Crohn's …, 2021 - academic.oup.com
Abstract Background and Aims The inflammatory bowel diseases [IBD], Crohn's disease and
ulcerative colitis, are chronic, idiopathic gastrointestinal diseases. Although their precise …

NMR-based metabolomics in human disease diagnosis: applications, limitations, and recommendations

AHM Emwas, RM Salek, JL Griffin, J Merzaban - Metabolomics, 2013 - Springer
Metabolomics is a dynamic and emerging research field, similar to proteomics,
transcriptomics and genomics in affording global understanding of biological systems. It is …

Microbiome, metabolome and inflammatory bowel disease

I Ahmed, BC Roy, SA Khan, S Septer, S Umar - Microorganisms, 2016 - mdpi.com
Inflammatory Bowel Disease (IBD) is a multifactorial disorder that conceptually occurs as a
result of altered immune responses to commensal and/or pathogenic gut microbes in …

Alterations in lipid, amino acid, and energy metabolism distinguish Crohn's disease from ulcerative colitis and control subjects by serum metabolomic profiling

EA Scoville, MM Allaman, CT Brown, AK Motley… - Metabolomics, 2018 - Springer
Introduction Biomarkers are needed in inflammatory bowel disease (IBD) to help define
disease activity and identify underlying pathogenic mechanisms. We hypothesized that …

Metabonomics of human fecal extracts characterize ulcerative colitis, Crohn's disease and healthy individuals

JT Bjerrum, Y Wang, F Hao, M Coskun, C Ludwig… - Metabolomics, 2015 - Springer
This study employs spectroscopy-based metabolic profiling of fecal extracts from healthy
subjects and patients with active or inactive ulcerative colitis (UC) and Crohn's disease (CD) …

[HTML][HTML] Protein fermentation in the gut; implications for intestinal dysfunction in humans, pigs, and poultry

MS Gilbert, N Ijssennagger, AK Kies… - American Journal of …, 2018 - journals.physiology.org
The amount of dietary protein is associated with intestinal disease in different vertebrate
species. In humans, this is exemplified by the association between high-protein intake and …

Metabolic modelling reveals broad changes in gut microbial metabolism in inflammatory bowel disease patients with dysbiosis

A Heinken, J Hertel, I Thiele - NPJ systems biology and applications, 2021 - nature.com
Inflammatory bowel diseases, such as Crohn's Disease, are characterised by an altered
blood and faecal metabolome, and changes in gut microbiome composition. Here, we …

[HTML][HTML] Serum and urine metabolomic fingerprinting in diagnostics of inflammatory bowel diseases

T Dawiskiba, S Deja, A Mulak, A Ząbek… - World journal of …, 2014 - ncbi.nlm.nih.gov
AIM: To evaluate the utility of serum and urine metabolomic analysis in diagnosing and
monitoring of inflammatory bowel diseases (IBD). METHODS: Serum and urine samples …

Metabolomics insights into inflammatory bowel disease: a comprehensive review

L Aldars-Garcia, JP Gisbert, M Chaparro - Pharmaceuticals, 2021 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic, complex relapsing disorder characterised by
immune dysregulation, gut microbiota alteration, and disturbed intestinal permeability. The …