Abstract In 1959, Niels Lassen illustrated the cerebral autoregulation curve in the classic
review article entitled Cerebral Blood Flow and Oxygen Consumption in Man. This concept …

The global spread of COVID-19 has caused a substantial societal burden and become a
major global public health issue. The COVID-19 elderly population with hypertension …

The blood–brain barrier (BBB) helps maintain a tightly regulated microenvironment for
optimal central nervous system (CNS) homeostasis and facilitates communications with the …

Despite the plethora of published studies on intracranial aneurysms (IAs) hemodynamic
using computational fluid dynamics (CFD), limited progress has been made towards …

Intact, coordinated, and precisely regulated cerebrovascular responses are required for the
maintenance of cerebral metabolic homeostasis, adequate perfusion, oxygen delivery, and …

COVID-19 respiratory failure is a life-threatening condition. Oxygenation targets were
evaluated in a non-ICU setting. In this retrospective, observational study, we enrolled all …

Cerebrovascular reactivity (CVR), is important for determining future risk of cerebrovascular
disease. It is unclear if primary aging is associated with reductions in CVR because previous …

Although the human cerebral circulation is richly innervated with sympathetic nerve fibers,
the role of sympathetic nerve activity (SNA) on the regulation of cerebral blood flow (CBF) …

Ascent to high-altitude elicits compensatory physiological adaptations in order to improve
oxygenation throughout the body. The brain is particularly vulnerable to the hypoxemia of …

Restoring perfusion to ischemic tissue is the primary goal of acute ischemic stroke care, yet
only a small portion of patients receive reperfusion treatment. Since blood pressure (BP) is …