A Razor's Edge: Vascular Responses to Acute Inflammatory Lung Injury/Acute Respiratory Distress Syndrome
DR Price, JGN Garcia - Annual Review of Physiology, 2024 - annualreviews.org
Historically considered a metabolically inert cellular layer separating the blood from the
underlying tissue, the endothelium is now recognized as a highly dynamic, metabolically …
underlying tissue, the endothelium is now recognized as a highly dynamic, metabolically …
“Severity” in adult sickle cell disease
MH Steinberg, MT Gladwin - American Journal of Hematology, 2023 - Wiley Online Library
More than 50 years ago patients with sickle cell anemia surviving to adulthood with few
acute painful events were deemed “mild” or “relatively benign.” 1, 2 Their clinical course …
acute painful events were deemed “mild” or “relatively benign.” 1, 2 Their clinical course …
Doubling down on PK activation for sickle cell disease
SR Wilson, LH Pecker - Blood Advances, 2024 - ashpublications.org
In this issue of Blood Advances, Saraf et al 1 report the results of the phase 1 multicenter,
randomized, placebo-controlled study of etavopivat, a pyruvate kinase (PK) activator, under …
randomized, placebo-controlled study of etavopivat, a pyruvate kinase (PK) activator, under …