Poly (A) tale: From A to A; RNA polyadenylation in prokaryotes and eukaryotes

A Mofayezi, M Jadaliha, F Zangeneh… - Wiley Interdisciplinary …, 2024 - Wiley Online Library
Most eukaryotic mRNAs and different non‐coding RNAs undergo a form of 3′ end
processing known as polyadenylation. Polyadenylation machinery is present in almost all …

Molecular Organization and Regulation of the Mammalian Synapse by the Post-Translational Modification SUMOylation

I Chato-Astrain, M Pronot, T Coppola, S Martin - Cells, 2024 - mdpi.com
Neurotransmission occurs within highly specialized compartments forming the active
synapse where the complex organization and dynamics of the interactions are tightly …

Applying Proteomics and Computational Approaches to Identify Novel Targets in Blast-Associated Post-Traumatic Epilepsy

JL Browning, KA Wilson, O Shandra, X Wei… - International Journal of …, 2024 - mdpi.com
Traumatic brain injury (TBI) can lead to post-traumatic epilepsy (PTE). Blast TBI (bTBI) found
in Veterans presents with several complications, including cognitive and behavioral …

Role of Post-Transcriptional Regulation in Learning and Memory in Mammals

CM Di Liegro, G Schiera, G Schirò, I Di Liegro - Genes, 2024 - mdpi.com
After many decades, during which most molecular studies on the regulation of gene
expression focused on transcriptional events, it was realized that post-transcriptional control …

CPEB2 inhibits preeclampsia progression by regulating SSTR3 translation through polyadenylation

Y Zhao, L Zhang, J Yang, C Li, P Li - Biochimica et Biophysica Acta (BBA) …, 2024 - Elsevier
Aims Trophoblast cell dysfunction is one of the important factors leading to preeclampsia
(PE). Cytoplasmic polyadenylation element-binding 2 (CPEB2) has been found to be …

Electroacupuncture Pretreatment Attenuates Learning Memory Impairment Induced by Repeated Propofol Exposure and Modulates Hippocampal Synaptic Plasticity …

S Fan, X Wang, N Gao, S Wei - Journal of Inflammation Research, 2023 - Taylor & Francis
Background Recurrent propofol anesthesia in the peak of neurodevelopment may lead to
learning-memory decline. This study aimed to examine the efficacy of electroacupuncture …

Orb2 enables rare-codon-enriched mRNA expression during Drosophila neuron differentiation

RK Stewart, P Nguyen, A Laederach, PC Volkan… - bioRxiv, 2023 - biorxiv.org
Regulation of codon optimality is an increasingly appreciated layer of cell-and tissue-
specific protein expression control. Here, we use codon-modified reporters to show that …