Total knee arthroplasty (TKA) is a highly successful operation that improves patients' quality
of life and functionality. Yet, up to 20% of TKA patients remain unsatisfied with the functional …

Osteoarthritis (OA) is a leading cause of disability, globally. Despite an emerging role for
synovial inflammation in OA pathogenesis, attempts to target inflammation therapeutically …

Background and purpose—Up to 20% of patients are dissatisfied after total knee
arthroplasty (TKA), mainly because of pain and restricted physical function. We developed a …

Engineering biomechanical features of total knee arthroplasty (TKA) have been investigated
by many researchers with theoretical and empirical development extensively fulfilled in the …

Purpose Over the last decade, robotic TKA gained popularity for improving the accuracy of
implant positioning and reducing outliers in limb alignment comparing to conventional jig …

Background Robotic assisted total knee arthroplasty (RTKA) has shown improved knee
alignment and reduced radiographic outliers. However, there remains debate on functional …

Patient-reported outcome measures (PROMs) are being used increasingly in total knee
arthroplasty (TKA). We conducted a systematic review aimed at identifying psychometrically …

Background The minimum clinically important difference (MCID) is intended to detect a
change in a patient-reported outcome measure (PROM) large enough for a patient to …

Excellent durability with traditional jig-based manual total knee arthroplasty (mTKA) has
been noted, but substantial rates of dissatisfaction remain. Robotic-assisted TKA (raTKA) …

Background Depression has been implicated as a poor predictor of outcomes after total joint
arthroplasty (TJA) of the lower extremity in some studies. We aimed to determine whether …