There is much interest in the use of extracellular vesicles (EVs) as a subcellular therapy for
regenerative medicine and drug delivery. Blood-borne platelets represent a source of …

Previously thought to be nothing more than cellular debris, extracellular vesicles (EVs) are
now known to mediate physiological and pathological functions throughout the body. We …

Platelets are small anucleated blood cells primarily known for their vital hemostatic role.
Allogeneic platelet concentrates (PCs) collected from healthy donors are an essential …

The physiological heterogeneity of platelets leads to diverse responses and the formation of
discrete subpopulations upon platelet stimulation. Procoagulant platelets are an example of …

Cell-free mitochondrial DNA (cf-mtDNA) is a marker of inflammatory disease and a predictor
of mortality, but little is known about cf-mtDNA in relation to psychobiology. A systematic …

The use of platelet-rich plasma (PRP) has gained increasing interest in recent decades. The
platelet secretome contains a multitude of growth factors, cytokines, chemokines, and other …

Platelets are a heterogeneous small anucleate blood cell population with a central role both
in physiological haemostasis and in pathological states, spanning from thrombosis to …

Extracellular vesicles (EVs) are cell‐derived particles with a phospholipid membrane
present in all body fluids. Because EV properties change in health and disease, EVs have …

Extracellular vesicles (EVs) are composed of a lipid bilayer containing transmembrane and
soluble proteins. Subtypes of EVs include ectosomes (microparticles/microvesicles) …

Extracellular vesicles (EVs) are nanoparticles released from various cell types that have
emerged as powerful new therapeutic option for a variety of diseases. EVs are involved in …