Pathogenesis and treatment options of cancer related anemia: perspective for a targeted mechanism-based approach

C Madeddu, G Gramignano, G Astara… - Frontiers in …, 2018 - frontiersin.org
Cancer-related anemia (CRA) is a common sign occurring in more than 30% of cancer
patients at diagnosis before the initiation of antineoplastic therapy. CRA has a relevant …

[HTML][HTML] Malnutrition in cirrhosis: More food for thought

B Chapman, M Sinclair, PJ Gow… - World journal of …, 2020 - ncbi.nlm.nih.gov
Malnutrition is highly prevalent in liver cirrhosis and its presence carries important
prognostic implications. The clinical conditions and pathophysiological mechanisms that …

Diagnosing pediatric malnutrition: paradigm shifts of etiology‐related definitions and appraisal of the indicators

S Bouma - Nutrition in Clinical Practice, 2017 - Wiley Online Library
The publication of the landmark paper “Defining Pediatric Malnutrition: A Paradigm Shift
Toward Etiology‐Related Definitions” launched a new era in diagnosing pediatric …

How does the social environment 'get into the mind'? Epigenetics at the intersection of social and psychiatric epidemiology

S Toyokawa, M Uddin, KC Koenen, S Galea - Social science & medicine, 2012 - Elsevier
The social environment plays a considerable role in determining major psychiatric disorders.
Emerging evidence suggests that features of the social environment modify gene expression …

Peroxisome proliferator-activated receptors and caloric restriction—common pathways affecting metabolism, health, and longevity

K Duszka, A Gregor, H Guillou, J König, W Wahli - Cells, 2020 - mdpi.com
Caloric restriction (CR) is a traditional but scientifically verified approach to promoting health
and increasing lifespan. CR exerts its effects through multiple molecular pathways that …

Inflammation, appetite and food intake in older hospitalized patients

L Sieske, G Janssen, N Babel, TH Westhoff, R Wirth… - Nutrients, 2019 - mdpi.com
The effect of inflammation on appetite and food intake has been rarely studied in humans. In
this study, we examined the association of C-reactive protein (CRP), as an inflammatory …

Impact of prebiotics on metabolic and behavioral alterations in a mouse model of metabolic syndrome

LF De Cossio, C Fourrier, J Sauvant, A Everard… - Brain, behavior, and …, 2017 - Elsevier
Mounting evidence shows that the gut microbiota, an important player within the gut-brain
communication axis, can affect metabolism, inflammation, brain function and behavior …

A bed nucleus of stria terminalis microcircuit regulating inflammation-associated modulation of feeding

Y Wang, JM Kim, MB Schmit, TS Cho, C Fang… - Nature …, 2019 - nature.com
Loss of appetite or anorexia associated with inflammation impairs quality of life and
increases morbidity in many diseases. However, the exact neural mechanism that mediates …

Cancer related anemia: an integrated multitarget approach and lifestyle interventions

V Natalucci, E Virgili, F Calcagnoli, G Valli, D Agostini… - Nutrients, 2021 - mdpi.com
Cancer is often accompanied by worsening of the patient's iron profile, and the resulting
anemia could be a factor that negatively impacts antineoplastic treatment efficacy and …

Sickness: from the focus on cytokines, prostaglandins, and complement factors to the perspectives of neurons

DCH Poon, YS Ho, K Chiu, HL Wong… - … & biobehavioral reviews, 2015 - Elsevier
Systemic inflammation leads to a variety of physiological (eg fever) and behavioral (eg
anorexia, immobility, social withdrawal, depressed mood, disturbed sleep) responses that …