Acne in the first three decades of life: An update of a disorder with profound implications for all decades of life
DE Greydanus, R Azmeh, MD Cabral, CA Dickson… - Disease-a-Month, 2021 - Elsevier
Acne vulgaris is a chronic, inflammatory, skin condition that involves the pilosebaceous
follicles and is influenced by a variety of factors including genetics, androgen-stimulation of …
follicles and is influenced by a variety of factors including genetics, androgen-stimulation of …
Adolescent acne vulgaris: current and emerging treatments
AM Layton, J Ravenscroft - The Lancet Child & Adolescent Health, 2023 - thelancet.com
Acne vulgaris is one of the commonest inflammatory skin diseases seen worldwide, affecting
all ethnicities and races, with a peak prevalence between age 15 years and 20 years. The …
all ethnicities and races, with a peak prevalence between age 15 years and 20 years. The …
Metformin restores tetracyclines susceptibility against multidrug resistant bacteria
Highly persistent incidence of multidrug resistant (MDR) bacterial pathogens constitutes a
global burden for public health. An alternative strategy to alleviate such a crisis is to identify …
global burden for public health. An alternative strategy to alleviate such a crisis is to identify …
[HTML][HTML] Insulin resistance and acne: the role of metformin as alternative therapy in men
A Andreadi, S Muscoli, R Tajmir, M Meloni, A Minasi… - Pharmaceuticals, 2022 - mdpi.com
The association between acne and insulin resistance has not been investigated as
thoroughly in males as it has been in women, despite the fact that in adult men, acne …
thoroughly in males as it has been in women, despite the fact that in adult men, acne …
Metformin has anti-inflammatory effects and induces immunometabolic reprogramming via multiple mechanisms in hidradenitis suppurativa
A Petrasca, R Hambly, N Kearney… - British Journal of …, 2023 - academic.oup.com
Background Targeting immunometabolism has shown promise in treating autoimmune and
inflammatory conditions. Hidradenitis suppurativa (HS) is a chronic inflammatory skin …
inflammatory conditions. Hidradenitis suppurativa (HS) is a chronic inflammatory skin …
[HTML][HTML] A molecular perspective on the potential benefits of metformin for the treatment of inflammatory skin disorders
JE Chang, MS Choi - International Journal of Molecular Sciences, 2020 - mdpi.com
Due to its anti-hyperglycemic effect, metformin is the first-line medication for the treatment of
type 2 diabetes, particularly in people who are obese. However, metformin is a drug with a …
type 2 diabetes, particularly in people who are obese. However, metformin is a drug with a …
Clinical experience and psychometric properties of the Cardiff Acne Disability Index (CADI)
YT Abdelrazik, FM Ali, MS Salek… - British Journal of …, 2021 - academic.oup.com
Summary The Cardiff Acne Disability Index (CADI) is a questionnaire designed to measure
the quality of life of teenagers and young adults with acne. It has been used clinically and …
the quality of life of teenagers and young adults with acne. It has been used clinically and …
[HTML][HTML] Insulin resistance in patients with acne vulgaris
M Gruszczyńska, A Sadowska-Przytocka, W Szybiak… - Biomedicines, 2023 - mdpi.com
Acne vulgaris presents multifactorial pathogenesis, which may include insulin resistance. To
investigate whether insulin resistance is a causative factor in acne vulgaris development …
investigate whether insulin resistance is a causative factor in acne vulgaris development …
Acne treatments: future trajectories
C Dessinioti, B Dreno - Clinical and Experimental Dermatology, 2020 - academic.oup.com
Current acne treatments present several limitations, posing the need for new effective
therapies for long‐term administration for recalcitrant or relapsing acne. Key players in acne …
therapies for long‐term administration for recalcitrant or relapsing acne. Key players in acne …
Non-conventional therapeutical approaches to acne vulgaris related to its association with metabolic disorders
The ever-increasing frequency of metabolic syndrome (MetS) is still a major challenge of the
public health care system, worldwide. In recent years, researchers have been drawn to the …
public health care system, worldwide. In recent years, researchers have been drawn to the …