Model validation and selection in metabolic flux analysis and flux balance analysis

AA Shehata, HR El-Seedi, G Tellez-Isaias… - Ger. J. Vet …, 2024 - researchgate.net

Metabolomics is a bottom-up approach to studying metabolism in living cells, tissues,
organoids, or even whole organisms. In conjunction with genomics and proteomics, it is a …

Metabolic models predict fotemustine and the combination of eflornithine/rifamycin and adapalene/cannabidiol for the treatment of gliomas

A Kishk, M Pires Pacheco, T Heurtaux… - Briefings in …, 2024 - academic.oup.com

Gliomas are the most common type of malignant brain tumors, with glioblastoma multiforme
(GBM) having a median survival of 15 months due to drug resistance and relapse. The …

HMT: Hybrid mechanistic Transformer for bio-fabrication prediction under complex environmental conditions

Y Song, H Xu, C Li, Q He, Z Tian, X Liu - Expert Systems with Applications, 2024 - Elsevier

In the field of bio-manufacturing, hybrid models that combine mechanistic models with data-
driven models have not been widely adopted. This is primarily due to the complexity of the …

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[HTML] mdpi.com

[HTML][HTML] Pitfalls in Metaheuristics Solving Stoichiometric-Based Optimization Models for Metabolic Networks

MF Briones-Báez, L Aguilera-Vázquez… - Algorithms, 2024 - mdpi.com

Flux Balance Analysis (FBA) is a constraint-based method that is commonly used to guide
metabolites through restricting pathways that often involve conditions such as anaplerotic …

[PDF] rsmu.press

[PDF][PDF] МНЕНИЕ БИОТЕХНОЛОГИЯ

Б БЕЛКОВ - Bulletin of Russian State Medical University - vestnik.rsmu.press

Повышение эффективности производства биотерапевтических препаратов—одна из
ключевых задач современной фармацевтики. В зависимости от желаемого состава …