Omega-3 long-chain polyunsaturated fatty acids: Metabolism and health implications

I Khan, M Hussain, B Jiang, L Zheng, Y Pan, J Hu… - Progress in lipid …, 2023 - Elsevier
Abstract Recently, omega-3 long-chain polyunsaturated fatty acids (n-3 LC-PUFAs) have
gained substantial interest due to their specific structure and biological functions. Humans …

[HTML][HTML] Functional behavior of DHA and EPA in the formation of babies brain at different stages of age, and protect from different brain-related diseases

W Khalid, P Gill, MS Arshad, A Ali… - … Journal of Food …, 2022 - Taylor & Francis
Omega-3 fatty acids are rich in marine animals and plant-based foods like grains and seeds.
Docosahexaenoic acid (DHA) and Eicosapentaenoic acid (EPA) are directly present in …

Arachidonic acid metabolism in health and disease

Y Zhang, Y Liu, J Sun, W Zhang, Z Guo, Q Ma - MedComm, 2023 - Wiley Online Library
Arachidonic acid (AA), an n‐6 essential fatty acid, is a major component of mammalian cells
and can be released by phospholipase A2. Accumulating evidence indicates that AA plays …

Maternal PUFAs, placental epigenetics, and their relevance to fetal growth and brain development

S Basak, AK Duttaroy - Reproductive Sciences, 2023 - Springer
Dietary polyunsaturated fatty acids (PUFAs), especially omega-3 (n-3) and n-6 long-chain
(LC) PUFAs, are indispensable for the fetus' brain supplied by the placenta. Despite being …

Prenatal THC exposure induces long-term, sex-dependent cognitive dysfunction associated with lipidomic and neuronal pathology in the prefrontal cortex …

MH Sarikahya, SL Cousineau, M De Felice… - Molecular …, 2023 - nature.com
With increasing maternal cannabis use, there is a need to investigate the lasting impact of
prenatal exposure to Δ9-tetrahydrocannabinol (THC), the main psychotropic compound in …

[HTML][HTML] Maternal fatty acid metabolism in pregnancy and its consequences in the feto-placental development

AK Duttaroy, S Basak - Frontiers in Physiology, 2022 - frontiersin.org
During pregnancy, maternal plasma fatty acids are critically required for cell growth and
development, cell signaling, and the development of critical structural and functional aspects …

[HTML][HTML] Dietary Implications of Polyunsaturated Fatty Acids during Pregnancy and in Neonates

E Herrera, H Ortega-Senovilla - Life, 2023 - mdpi.com
Certain limitations exist for animals to modify fatty acid changes. Besides the role of
arachidonic acid (AA), docosahexaenoic acid (DHA) and other 20-carbon long-chain …

[HTML][HTML] Targeting fatty acid uptake and metabolism in cancer cells: A promising strategy for cancer treatment

R Mallick, P Bhowmik, AK Duttaroy - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Despite scientific development, cancer is still a fatal disease. The development of cancer is
thought to be significantly influenced by fatty acids. Several mechanisms that control fatty …

Comparative plasma metabolomic analysis to identify biomarkers for lead-induced cognitive impairment

Y Wang, Y Nong, X Zhang, T Mai, J Cai, J Liu… - Chemico-Biological …, 2022 - Elsevier
Abstract Background Lead (Pb), an environmental neurotoxicant, is known to induce
cognitive impairment. Neuroinflammation and oxidative stress in the brain tissue are …

[HTML][HTML] Embryonic arsenic exposure triggers long-term behavioral impairment with metabolite alterations in zebrafish

N Abu Bakar, WN Wan Ibrahim, CA Che Abdullah… - Toxics, 2022 - mdpi.com
Arsenic trioxide (As2O3) is a ubiquitous heavy metal in the environment. Exposure to this
toxin at low concentrations is unremarkable in developing organisms. Nevertheless …