The human stress response
G Russell, S Lightman - Nature reviews endocrinology, 2019 - nature.com
The human stress response has evolved to maintain homeostasis under conditions of real or
perceived stress. This objective is achieved through autoregulatory neural and hormonal …
perceived stress. This objective is achieved through autoregulatory neural and hormonal …
The self in context: brain systems linking mental and physical health
Increasing evidence suggests that mental health and physical health are linked by neural
systems that jointly regulate somatic physiology and high-level cognition. Key systems …
systems that jointly regulate somatic physiology and high-level cognition. Key systems …
Cancer-related fatigue—mechanisms, risk factors, and treatments
JE Bower - Nature reviews Clinical oncology, 2014 - nature.com
Fatigue is one of the most common adverse effects of cancer that might persist for years after
treatment completion in otherwise healthy survivors. Cancer-related fatigue causes …
treatment completion in otherwise healthy survivors. Cancer-related fatigue causes …
The role of pro-inflammatory cytokines in neuroinflammation, neurogenesis and the neuroendocrine system in major depression
YK Kim, KS Na, AM Myint, BE Leonard - Progress in Neuro …, 2016 - Elsevier
Cytokines are pleiotropic molecules with important roles in inflammatory responses. Pro-
inflammatory cytokines and neuroinflammation are important not only in inflammatory …
inflammatory cytokines and neuroinflammation are important not only in inflammatory …
Infection risk and safety of corticosteroid use
J Youssef, SA Novosad… - Rheumatic Disease …, 2016 - rheumatic.theclinics.com
Because of their potent anti-inflammatory properties, corticosteroids have been used for
decades to treat many diseases, including rheumatic diseases. They are frequently used in …
decades to treat many diseases, including rheumatic diseases. They are frequently used in …
Glucocorticoid regulation of inflammation and its functional correlates: from HPA axis to glucocorticoid receptor dysfunction
MN Silverman, EM Sternberg - … of the new York Academy of …, 2012 - Wiley Online Library
Enhanced susceptibility to inflammatory and autoimmune disease can be related to
impairments in HPA axis activity and associated hypocortisolism, or to glucocorticoid …
impairments in HPA axis activity and associated hypocortisolism, or to glucocorticoid …
11β-hydroxysteroid dehydrogenases: intracellular gate-keepers of tissue glucocorticoid action
Glucocorticoid action on target tissues is determined by the density of “nuclear” receptors
and intracellular metabolism by the two isozymes of 11β-hydroxysteroid dehydrogenase …
and intracellular metabolism by the two isozymes of 11β-hydroxysteroid dehydrogenase …
Biological mechanisms underlying the role of physical fitness in health and resilience
MN Silverman, PA Deuster - Interface focus, 2014 - royalsocietypublishing.org
Physical fitness, achieved through regular exercise and/or spontaneous physical activity,
confers resilience by inducing positive psychological and physiological benefits, blunting …
confers resilience by inducing positive psychological and physiological benefits, blunting …
[HTML][HTML] The anti-inflammatory and immunosuppressive effects of glucocorticoids, recent developments and mechanistic insights
AE Coutinho, KE Chapman - Molecular and cellular endocrinology, 2011 - Elsevier
Since the discovery of glucocorticoids in the 1940s and the recognition of their anti-
inflammatory effects, they have been amongst the most widely used and effective treatments …
inflammatory effects, they have been amongst the most widely used and effective treatments …
How do glucocorticoids influence stress responses? Integrating permissive, suppressive, stimulatory, and preparative actions
RM Sapolsky, LM Romero, AU Munck - Endocrine reviews, 2000 - academic.oup.com
The secretion of glucocorticoids (GCs) is a classic endocrine response to stress. Despite
that, it remains controversial as to what purpose GCs serve at such times. One view …
that, it remains controversial as to what purpose GCs serve at such times. One view …