[HTML][HTML] Sporadic medullary thyroid carcinoma: towards a precision medicine
A Matrone, C Gambale, A Prete, R Elisei - Frontiers in Endocrinology, 2022 - frontiersin.org
Medullary thyroid carcinoma (MTC) is a neuroendocrine malignant tumor originating from
parafollicular C-cells producing calcitonin. Most of cases (75%) are sporadic while the …
parafollicular C-cells producing calcitonin. Most of cases (75%) are sporadic while the …
[HTML][HTML] The impact of the BCR-ABL oncogene in the pathology and treatment of chronic myeloid leukemia
Abstract Chronic Myeloid Leukemia (CML) is characterized by chromosomal aberrations
involving the fusion of the BCR and ABL genes on chromosome 22, resulting from a …
involving the fusion of the BCR and ABL genes on chromosome 22, resulting from a …
[HTML][HTML] Growth inhibitory and pro-apoptotic effects of hirsuteine in chronic myeloid leukemia cells through targeting sphingosine kinase 1
S Gao, T Guo, S Luo, Y Zhang, Z Ren… - Biomolecules & …, 2022 - ncbi.nlm.nih.gov
Chronic myeloid leukemia (CML) is a slowly progressing hematopoietic cell disorder.
Sphingosine kinase 1 (SPHK1) plays established roles in tumor initiation, progression, and …
Sphingosine kinase 1 (SPHK1) plays established roles in tumor initiation, progression, and …
[HTML][HTML] Bullous Pemphigoid Occurring after Stopping Imatinib Therapy of CML: Is a Continuation of Post-Treatment Follow-Up Needed?
A Yakobson, AE Neime, O Abu Saleh, K Al Athamen… - Clinics and …, 2023 - mdpi.com
Advancements and the use of tyrosine kinase inhibitors (TKIs) have revolutionized the
treatment of Chronic Myeloid Leukemia (CML), achieving unprecedented success rates and …
treatment of Chronic Myeloid Leukemia (CML), achieving unprecedented success rates and …
[HTML][HTML] The m6A regulator KIAA1429 stabilizes RAB27B mRNA and promotes the progression of chronic myeloid leukemia and resistance to targeted therapy
F Yao, F Zhong, J Jiang, Y Cheng, S Xu, J Liu, J Lin… - Genes & …, 2024 - Elsevier
Chronic myeloid leukemia (CML) is a common adult leukemia. Both the acute phase of the
disease and the adverse effects of anti-cancer treatments can lead to a poor prognosis. The …
disease and the adverse effects of anti-cancer treatments can lead to a poor prognosis. The …
Mechanism of procyanidin b2 in the treatment of chronic myeloid leukemia based on integrating network pharmacology and molecular docking
HX Li, YX Jing, YH Chai, XH Sun, XX He… - Anti-Cancer Agents …, 2023 - ingentaconnect.com
Objective: To study the pharmacological mechanism of procyanidin B2 (PCB2) on chronic
myeloid leukemia (CML) by integrating network pharmacological methods systematically …
myeloid leukemia (CML) by integrating network pharmacological methods systematically …
Exploring the interaction of tepotinib with calf thymus DNA using molecular dynamics simulation and multispectroscopic techniques
M Amir, MA Qureshi, A Khan, SM Nayeem… - … Acta Part A: Molecular …, 2024 - Elsevier
In recent times, there has been a surge in the discovery of drugs that directly interact with
DNA, influencing gene expression. As a result, understanding how biomolecules interact …
DNA, influencing gene expression. As a result, understanding how biomolecules interact …
[HTML][HTML] 异常DNA 甲基化在慢性髓系白血病中的临床应用
周灵艳， 殷小成 - Journal of Central South University Medical …, 2024 - ncbi.nlm.nih.gov
Abstract DNA 甲基化是一种人体内重要的生物化学过程， 即在不改变DNA 序列的情况下，
基因表达发生可稳定遗传的变化。 DNA 甲基化状态的改变与众多生物过程有着紧密的关联 …
基因表达发生可稳定遗传的变化。 DNA 甲基化状态的改变与众多生物过程有着紧密的关联 …
[HTML][HTML] Hypertension in Cardio-Oncology Clinic: an update on etiology, assessment, and management
Hypertension is one of the most common comorbidity and the leading cause of cancer-
related death in cancer patients. The prevalence of hypertension in cancer patients is much …
related death in cancer patients. The prevalence of hypertension in cancer patients is much …
Mechanism of salidroside in the treatment of chronic myeloid leukemia based on the network pharmacology and molecular docking
Y Chai, F Chen, Z Li, P Yang, Q Zhou, W Liu… - Clinical and Translational …, 2023 - Springer
Background Salidroside is a phenolic natural product, which is a kind of Rhodiola rosea. It
has been confirmed that it has inhibitory effects on chronic myeloid leukemia, but the specific …
has been confirmed that it has inhibitory effects on chronic myeloid leukemia, but the specific …