Ghrelin and glucagon-like peptide-1: a gut-brain axis battle for food reward

L Decarie-Spain, SE Kanoski - Nutrients, 2021 - mdpi.com
Eating behaviors are influenced by the reinforcing properties of foods that can favor
decisions driven by reward incentives over metabolic needs. These food reward-motivated …

The intriguing ligand-dependent and ligand-independent actions of the growth hormone secretagogue receptor on reward-related behaviors

MP Cornejo, ER Mustafá, F Barrile, D Cassano… - Neuroscience & …, 2021 - Elsevier
The growth hormone secretagogue receptor (GHSR) is a G-protein-coupled receptor
(GPCR) highly expressed in the brain, and also in some peripheral tissues. GHSR activity is …

Gut peptide regulation of food intake–evidence for the modulation of hedonic feeding

ORM Woodward, FM Gribble… - The Journal of …, 2022 - Wiley Online Library
The number of people living with obesity has tripled worldwide since 1975 with serious
implications for public health, as obesity is linked to a significantly higher chance of early …

Neuropeptides modulate feeding via the dopamine reward pathway

R Jin, S Sun, Y Hu, H Zhang, X Sun - Neurochemical Research, 2023 - Springer
Dopamine (DA) is a catecholamine neurotransmitter widely distributed in the central nervous
system. It participates in various physiological functions, such as feeding, anxiety, fear …

Photoactive intragastric satiety-inducing device using polymeric photosensitizers for minimally invasive weight loss treatment

JW Kim, S Lee, DS Ryu, J Park, H Lee, HK Na, JH Noh… - Biomaterials, 2023 - Elsevier
An intragastric satiety-inducing device (ISD) located in the stomach induce satiety and
fullness in the absence of food by continuously pressing on the distal esophagus and cardia …

“Sibling” battle or harmony: crosstalk between nesfatin-1 and ghrelin

X Chen, J Dong, Q Jiao, X Du, M Bi, H Jiang - Cellular and Molecular Life …, 2022 - Springer
Ghrelin was first identified as an endogenous ligand of the growth hormone secretagogue
receptor (GHSR) in 1999, with the function of stimulating the release of growth hormone …

Hindbrain ghrelin and liver-expressed antimicrobial peptide 2, ligands for growth hormone secretagogue receptor, bidirectionally control food intake

HS Wald, MY Ghidewon… - American Journal of …, 2023 - journals.physiology.org
Hindbrain growth hormone secretagogue receptor (GHSR) agonism increases food intake,
yet the underlying neural mechanisms remain unclear. The functional effects of hindbrain …

Lateral parabrachial nucleus astrocytes control food intake

D Mishra, JE Richard, I Maric, OT Shevchouk… - Frontiers in …, 2024 - frontiersin.org
Food intake behavior is under the tight control of the central nervous system. Most studies to
date focus on the contribution of neurons to this behavior. However, although previously …

Functional and neurochemical identification of ghrelin receptor (GHSR)-expressing cells of the lateral parabrachial nucleus in mice

MV Le May, F Peris-Sampedro, I Stoltenborg… - Frontiers in …, 2021 - frontiersin.org
The lateral parabrachial nucleus (lPBN), located in the pons, is a well-recognized
anorexigenic center harboring, amongst others, the calcitonin gene-related peptide (CGRP) …

Roles of Ghrelin and Leptin in Body Mass Regulation under Food Restriction Based on the AMPK Pathway in the Red-Backed Vole, Eothenomys miletus, from …

Y Liu, T Jia, Y Ren, Z Wang, W Zhu - Animals, 2022 - mdpi.com
Simple Summary Animals can adapt to food shortages through phenotypic changes. In this
study, food restriction reduced the body mass, RMR, serum leptin level, and POMC and …