Molecular Insights into Burkholderia pseudomallei and Burkholderia mallei Pathogenesis
EE Galyov, PJ Brett, D DeShazer - Annual review of …, 2010 - annualreviews.org
Burkholderia pseudomallei and Burkholderia mallei are closely related gram-negative
bacteria that can cause serious diseases in humans and animals. This review summarizes …
bacteria that can cause serious diseases in humans and animals. This review summarizes …
The type III secretion system tip complex and translocon
CA Mueller, P Broz, GR Cornelis - Molecular microbiology, 2008 - Wiley Online Library
The type III secretion machinery of Gram‐negative bacteria, also known as the injectisome
or needle complex, is composed of a basal body spanning both bacterial membranes and …
or needle complex, is composed of a basal body spanning both bacterial membranes and …
The molecular and cellular basis of pathogenesis in melioidosis: how does Burkholderia pseudomallei cause disease?
NR Lazar Adler, B Govan, M Cullinane… - FEMS microbiology …, 2009 - academic.oup.com
Melioidosis, a febrile illness with disease states ranging from acute pneumonia or
septicaemia to chronic abscesses, was first documented by). The causative agent …
septicaemia to chronic abscesses, was first documented by). The causative agent …
[HTML][HTML] Melioidosis: clinical impact and public health threat in the tropics
R Perumal Samy, BG Stiles, G Sethi… - PLoS neglected tropical …, 2017 - journals.plos.org
This review briefly summarizes the geographical distribution and clinical impact of
melioidosis, especially in the tropics. Burkholderia pseudomallei (a gram-negative …
melioidosis, especially in the tropics. Burkholderia pseudomallei (a gram-negative …
A naturally derived outer-membrane vesicle vaccine protects against lethal pulmonary Burkholderia pseudomallei infection
W Nieves, S Asakrah, O Qazi, KA Brown, J Kurtz… - Vaccine, 2011 - Elsevier
Burkholderia pseudomallei, and other members of the Burkholderia, are among the most
antibiotic-resistant bacterial species encountered in human infection. Mortality rates …
antibiotic-resistant bacterial species encountered in human infection. Mortality rates …
[HTML][HTML] Melioidosis vaccines: a systematic review and appraisal of the potential to exploit biodefense vaccines for public health purposes
Background Burkholderia pseudomallei is a Category B select agent and the cause of
melioidosis. Research funding for vaccine development has largely considered protection …
melioidosis. Research funding for vaccine development has largely considered protection …
[HTML][HTML] Development of Burkholderia mallei and pseudomallei vaccines
Burkholderia mallei and Burkholderia pseudomallei are Gram-negative bacteria that cause
glanders and melioidosis, respectively. Inhalational infection with either organism can result …
glanders and melioidosis, respectively. Inhalational infection with either organism can result …
[HTML][HTML] Immunospecific Responses to Bacterial Elongation Factor Tu during Burkholderia Infection and Immunization
W Nieves, J Heang, S Asakrah, K Höner zu Bentrup… - PloS one, 2010 - journals.plos.org
Burkholderia pseudomallei is the etiological agent of melioidosis, a disease endemic in
parts of Southeast Asia and Northern Australia. Currently there is no licensed vaccine …
parts of Southeast Asia and Northern Australia. Currently there is no licensed vaccine …
[HTML][HTML] Type III Secretion in the Melioidosis Pathogen Burkholderia pseudomallei
CW Vander Broek, JM Stevens - Frontiers in cellular and infection …, 2017 - frontiersin.org
Burkholderia pseudomallei is a Gram-negative intracellular pathogen and the causative
agent of melioidosis, a severe disease of both humans and animals. Melioidosis is an …
agent of melioidosis, a severe disease of both humans and animals. Melioidosis is an …
[HTML][HTML] Deoxycholate interacts with IpaD of Shigella flexneri in inducing the recruitment of IpaB to the type III secretion apparatus needle tip
KF Stensrud, PR Adam, CD La Mar, AJ Olive… - Journal of Biological …, 2008 - ASBMB
Type III secretion (TTS) is an essential virulence function for Shigella flexneri that delivers
effector proteins that are responsible for bacterial invasion of intestinal epithelial cells. The …
effector proteins that are responsible for bacterial invasion of intestinal epithelial cells. The …