Emerging SARS‐CoV‐2 variants can potentially break set epidemiological barriers in COVID‐19
Young age, female sex, absence of comorbidities, and prior infection or vaccination are
known epidemiological barriers for contracting the new infection and/or increased disease …
known epidemiological barriers for contracting the new infection and/or increased disease …
SARS‐CoV‐2 biology and variants: anticipation of viral evolution and what needs to be done
The global propagation of SARS‐CoV‐2 and the detection of a large number of variants,
some of which have replaced the original clade to become dominant, underscores the fact …
some of which have replaced the original clade to become dominant, underscores the fact …
Insights into the evolutionary and prophylactic analysis of SARS-CoV-2: A review
In late 2019, following the emergence of a β-originated SARS-CoV-2, phylogenetic and
evolutionary approaches have been demonstrated to strengthen the diagnostic and …
evolutionary approaches have been demonstrated to strengthen the diagnostic and …
Non-uniform aspects of the SARS-CoV-2 intraspecies evolution reopen question of its origin
Several hypotheses have been presented on the origin of severe acute respiratory
syndrome coronavirus-2 (SARS-CoV-2) from its identification as the agent causing the …
syndrome coronavirus-2 (SARS-CoV-2) from its identification as the agent causing the …
Effects of the 5′‐Triphosphate Metabolites of Ribavirin, Sofosbuvir, Vidarabine, and Molnupiravir on CTP Synthase Catalysis and Filament Formation: Implications for …
TD Gillis, SL Bearne - ChemMedChem, 2022 - Wiley Online Library
Repurposing of antiviral drugs affords a rapid and effective strategy to develop therapies to
counter pandemics such as COVID‐19. SARS‐CoV‐2 replication is closely linked to the …
counter pandemics such as COVID‐19. SARS‐CoV‐2 replication is closely linked to the …
EFFECTS OF 5′-TRIPHOSPHATE METABOLITES OF SPECIFIC ANTIVIRAL DRUGS ON CTP SYNTHASE ACTIVITY
T Gillis - 2021 - dalspace.library.dal.ca
Cytidine-5′-triphosphate (CTP) synthase (CTPS) catalyzes the biosynthesis of CTP from
UTP using either L-glutamine or free NH3 as a substrate. CTP is an essential precursor for …
UTP using either L-glutamine or free NH3 as a substrate. CTP is an essential precursor for …
Effects of the 5'‐Triphosphate Metabolites of Ribavirin, Sofosbuvir, Vidarabine, and Molnupiravir on CTP Synthase. Implications for Repurposing Antiviral Agents …
TD Gillis, SL Bearne - Chemmedchem, 2022 - ncbi.nlm.nih.gov
Repurposing of antiviral drugs affords a rapid and effective strategy to develop therapies to
counter pandemics such as COVID‐19. SARS‐CoV‐2 replication is closely linked to the …
counter pandemics such as COVID‐19. SARS‐CoV‐2 replication is closely linked to the …