Current molecular combination therapies used for the treatment of breast cancer

Y Wang, A Minden - International journal of molecular sciences, 2022 - mdpi.com
Breast cancer is the second leading cause of death for women worldwide. While
monotherapy (single agent) treatments have been used for many years, they are not always …

Using breast cancer gene expression signatures in clinical practice: unsolved issues, ongoing trials and future perspectives

R Varnier, C Sajous, S de Talhouet, C Smentek… - Cancers, 2021 - mdpi.com
Simple Summary Gene expression signatures were initially developed to take into account
tumor biology for adjuvant chemotherapy decision and have become a standard option in …

The DARC side of inflamm-aging: Duffy antigen receptor for chemokines (DARC/ACKR1) as a potential biomarker of aging, immunosenescence, and breast …

N Jinna, P Rida, T Su, Z Gong, S Yao, M LaBarge… - Cells, 2022 - mdpi.com
The proclivity of certain pre-malignant and pre-invasive breast lesions to progress while
others do not continues to perplex clinicians. Clinicians remain at a crossroads with …

Chemokine receptors differentially expressed by race category and molecular subtype in the breast cancer TCGA cohort

ED Vazquez, X Fang, LA Levesque, M Huynh… - Scientific Reports, 2022 - nature.com
Racial disparities in mortality due to metastasis remain significant among breast cancer
patients. Chemokine receptors contribute to breast tumors and metastatic outcome. We …

Ethnic disparities in the immune microenvironment of triple negative breast cancer and its role in therapeutic outcomes

KK Zajac, S Malla, RJ Babu, D Raman… - Cancer …, 2023 - Wiley Online Library
In 2020, newly diagnosed breast cancer (BC) cases surpassed that of lung cancer among
women, making it the most common female cancer globally. In spite of recent increases in …

Lipopolysaccharide from the commensal microbiota of the breast enhances cancer growth: role of S100A7 and TLR4

T Wilkie, AK Verma, H Zhao, M Charan… - Molecular …, 2022 - Wiley Online Library
The role of commensal bacterial microbiota in the pathogenesis of human malignancies has
been a research field of incomparable progress in recent years. Although breast tissue is …

A new prediction nomogram of non-sentinel lymph node metastasis in cT1-2 breast cancer patients with positive sentinel lymph nodes

L Yang, X Zhao, L Yang, Y Chang, C Cao, X Li… - Scientific Reports, 2024 - nature.com
We aimed to analyze the risk factors and construct a new nomogram to predict non-sentinel
lymph node (NSLN) metastasis for cT1-2 breast cancer patients with positivity after sentinel …

[HTML][HTML] Cyclin A2 and Ki-67 proliferation markers could be used to identify tumors with poor prognosis in African American women with breast cancer

D Beyene, T Naab, V Apprey, L Ricks-Santi… - Journal of cancer …, 2023 - ncbi.nlm.nih.gov
Background: Diagnosed invasive breast carcinomas in African American patients are more
aggressive compared with those in Caucasian patients and diagnosed at later stages of the …

Disparities in surgical oncology: management of advanced cancer

W Nizam, HL Yeo, S Obeng-Gyasi, MV Brock… - Annals of surgical …, 2021 - Springer
Significant variations in the patterns of care, incidence, and mortality rates of several
common cancers have been noted. These disparities have been attributed to a complex …

Resistin induces LIN28A-mediated let-7a repression in breast cancer cells leading to IL-6 and STAT3 upregulation

SK Deshmukh, SK Srivastava, H Zubair, MA Khan… - Cancers, 2021 - mdpi.com
Simple Summary Breast cancer is the second leading cause of cancer-related death in
women in the United States and exhibits significant racial disparities in clinical outcomes …