Pharmacological effects of cisplatin combination with natural products in cancer chemotherapy

S Dasari, S Njiki, A Mbemi, CG Yedjou… - International journal of …, 2022 - mdpi.com
Cisplatin and other platinum-based drugs, such as carboplatin, ormaplatin, and oxaliplatin,
have been widely used to treat a multitude of human cancers. However, a considerable …

Curcumin and colorectal cancer: from basic to clinical evidences

M Pricci, B Girardi, F Giorgio, G Losurdo… - International journal of …, 2020 - mdpi.com
Curcumin diffuses through cell membranes into the endoplasmic reticulum, mitochondria,
and nucleus, where it exerts actions, as an antioxidant property. Therefore, its use has been …

Anticancer properties of curcumin against colorectal cancer: a review

OA Ojo, TR Adeyemo, D Rotimi, GES Batiha… - Frontiers in …, 2022 - frontiersin.org
Colorectal cancer (CRC) is one of the most common and reoccurring diseases, as well as
the world's second largest cause of mortality. Despite existing preventative, diagnostic, and …

A functionalized graphene oxide with improved cytocompatibility for stimuli-responsive co-delivery of curcumin and doxorubicin in cancer treatment

F Yaghoubi, NSH Motlagh, SM Naghib… - Scientific Reports, 2022 - nature.com
Nowadays, the usage of nanoparticles in various fields such as drug delivery, attracts the
attention of many researchers in the treatment of cancers. Graphene oxide (GO) is one of the …

Plants as a source of anticancer agents: From bench to bedside

WH Talib, S Daoud, AI Mahmod, RA Hamed, D Awajan… - Molecules, 2022 - mdpi.com
Cancer is the second leading cause of death after cardiovascular diseases. Conventional
anticancer therapies are associated with lack of selectivity and serious side effects. Cancer …

Plant-derived natural products in cancer research: extraction, mechanism of action, and drug formulation

WH Talib, I Alsalahat, S Daoud, RF Abutayeh… - Molecules, 2020 - mdpi.com
Cancer is one of the main causes of death globally and considered as a major challenge for
the public health system. The high toxicity and the lack of selectivity of conventional …

Phytochemicals and gastrointestinal cancer: cellular mechanisms and effects to change cancer progression

RK Al-Ishaq, AJ Overy, D Büsselberg - Biomolecules, 2020 - mdpi.com
Gastrointestinal (GI) cancer is a prevailing global health disease with a high incidence rate
which varies by region. It is a huge economic burden on health care providers. GI cancer …

Pectin polymers for colon-targeted antitumor drug delivery

M Khotimchenko - International journal of biological macromolecules, 2020 - Elsevier
The use of chemotherapeutic drugs in the treatment of malignant tumors is always
associated with the severe side effects negatively affecting all organs and systems in human …

Mechanistic understanding of curcumin's therapeutic effects in lung cancer

WNB Wan Mohd Tajuddin, NH Lajis, F Abas, I Othman… - Nutrients, 2019 - mdpi.com
Lung cancer is among the most common cancers with a high mortality rate worldwide.
Despite the significant advances in diagnostic and therapeutic approaches, lung cancer …

[HTML][HTML] Inhibition of murine colorectal cancer metastasis by targeting M2-TAM through STAT3/NF-kB/AKT signaling using macrophage 1-derived extracellular vesicles …

TG de Carvalho, P Lara, C Jorquera-Cordero… - Biomedicine & …, 2023 - Elsevier
Colorectal cancer is still unmanageable despite advances in target therapy. However,
extracellular vesicles (EVs) have shown potential in nanomedicine as drug delivery systems …