Auto-regulatory feedback by RNA-binding proteins
M Müller-McNicoll, O Rossbach, J Hui… - Journal of molecular …, 2019 - academic.oup.com
RNA-binding proteins (RBPs) are key regulators in post-transcriptional control of gene
expression. Mutations that alter their activity or abundance have been implicated in …
expression. Mutations that alter their activity or abundance have been implicated in …
[HTML][HTML] Post-translational control of RNA-binding proteins and disease-related dysregulation
A Velázquez-Cruz, B Baños-Jaime… - Frontiers in molecular …, 2021 - frontiersin.org
Cell signaling mechanisms modulate gene expression in response to internal and external
stimuli. Cellular adaptation requires a precise and coordinated regulation of the transcription …
stimuli. Cellular adaptation requires a precise and coordinated regulation of the transcription …
Comprehensive identification of RNA–protein interactions in any organism using orthogonal organic phase separation (OOPS)
RML Queiroz, T Smith, E Villanueva… - Nature …, 2019 - nature.com
Existing high-throughput methods to identify RNA-binding proteins (RBPs) are based on
capture of polyadenylated RNAs and cannot recover proteins that interact with …
capture of polyadenylated RNAs and cannot recover proteins that interact with …
In vitro and in vivo RNA inhibition by CD9-HuR functionalized exosomes encapsulated with miRNA or CRISPR/dCas9
Z Li, X Zhou, M Wei, X Gao, L Zhao, R Shi, W Sun… - Nano …, 2018 - ACS Publications
In vitro and in vivo delivery of RNAs of interest holds promise for gene therapy. Recently,
exosomes are considered as a kind of rational vehicle for RNA delivery, especially miRNA …
exosomes are considered as a kind of rational vehicle for RNA delivery, especially miRNA …
KIAA1429 acts as an oncogenic factor in breast cancer by regulating CDK1 in an N6-methyladenosine-independent manner
JY Qian, J Gao, X Sun, MD Cao, L Shi, TS Xia… - Oncogene, 2019 - nature.com
Abstract Most N6-methyladenosine (m6A) associated regulatory proteins (ie, m6A writer,
eraser, and reader proteins) are involved in the pathogenesis of various cancers, mostly in …
eraser, and reader proteins) are involved in the pathogenesis of various cancers, mostly in …
POSTAR2: deciphering the post-transcriptional regulatory logics
Post-transcriptional regulation of RNAs is critical to the diverse range of cellular processes.
The volume of functional genomic data focusing on post-transcriptional regulation logics …
The volume of functional genomic data focusing on post-transcriptional regulation logics …
RNA-binding proteins and their role in kidney disease
L Seufert, T Benzing, M Ignarski… - Nature Reviews …, 2022 - nature.com
RNA-binding proteins (RBPs) are of fundamental importance for post-transcriptional gene
regulation and protein synthesis. They are required for pre-mRNA processing and for RNA …
regulation and protein synthesis. They are required for pre-mRNA processing and for RNA …
HuR-mediated nucleocytoplasmic translocation of HOTAIR relieves its inhibition of osteogenic differentiation and promotes bone formation
Y Li, W Sun, J Li, R Du, W Xing, X Yuan, G Zhong… - Bone Research, 2023 - nature.com
Bone marrow mesenchymal stem cell (BMSC) osteogenic differentiation and osteoblast
function play critical roles in bone formation, which is a highly regulated process. Long …
function play critical roles in bone formation, which is a highly regulated process. Long …
Functional extracellular vesicles for regenerative medicine
The unique biological characteristics and promising clinical potential of extracellular
vesicles (EVs) have galvanized EV applications for regenerative medicine. Recognized as …
vesicles (EVs) have galvanized EV applications for regenerative medicine. Recognized as …
[HTML][HTML] Emerging evidence of translational control by AU-rich element-binding proteins
H Otsuka, A Fukao, Y Funakami, KE Duncan… - Frontiers in …, 2019 - frontiersin.org
RNA-binding proteins (RBPs) are key regulators of posttranscriptional gene expression and
control many important biological processes including cell proliferation, development, and …
control many important biological processes including cell proliferation, development, and …