Neurofluids and the glymphatic system: anatomy, physiology, and imaging

DJJ Wang, J Hua, D Cao, ML Ho - The British journal of …, 2023 - academic.oup.com
First described in 2012, the glymphatic system is responsible for maintaining homeostasis
within the central nervous system, including nutrient delivery, waste clearance, and …

Vascular aspects of multiple sclerosis: emphasis on perfusion and cardiovascular comorbidities

D Jakimovski, M Topolski, AV Genovese… - Expert review of …, 2019 - Taylor & Francis
Introduction: Multiple sclerosis (MS) is a chronic inflammatory, demyelinating, and
neurodegenerative disease of the central nervous system. Over the last two decades, more …

Efficacy and safety of extracranial vein angioplasty in multiple sclerosis: a randomized clinical trial

P Zamboni, L Tesio, S Galimberti, L Massacesi… - JAMA …, 2018 - jamanetwork.com
Importance Chronic cerebrospinal venous insufficiency (CCSVI) is characterized by
restricted venous outflow from the brain and spinal cord. Whether this condition is …

A new hemodynamic model for the study of cerebral venous outflow

G Gadda, A Taibi, F Sisini… - American Journal …, 2015 - journals.physiology.org
We developed a mathematical model of the cerebral venous outflow for the simulation of the
average blood flows and pressures in the main drainage vessels of the brain. The main …

The prevalence of chronic cerebrospinal venous insufficiency in Meniere disease: 24-month follow-up after angioplasty

A Bruno, M Napolitano, L Califano, G Attanasio… - Journal of Vascular and …, 2017 - Elsevier
Purpose To evaluate relationship between Meniere disease (MD) and chronic cerebrospinal
venous insufficiency (CCSVI) using ultrasound, magnetic resonance (MR) imaging, and …

Effects of venous angioplasty on cerebral lesions in multiple sclerosis: expanded analysis of the brave dreams double-blind, sham-controlled randomized trial

P Zamboni, R Galeotti, F Salvi… - Journal of …, 2020 - journals.sagepub.com
Purpose: To evaluate if jugular vein flow restoration in various venographic defects
indicative of chronic cerebrospinal venous insufficiency (CCSVI) in multiple sclerosis (MS) …

[HTML][HTML] Why current Doppler ultrasound methodology is inaccurate in assessing cerebral venous return: the alternative of the ultrasonic jugular venous pulse

P Zamboni - Behavioural Neurology, 2016 - hindawi.com
Assessment of cerebral venous return is growing interest for potential application in clinical
practice. Doppler ultrasound (DUS) was used as a screening tool. However, three meta …

[HTML][HTML] Clinical classification and collateral circulation in chronic cerebrospinal venous insufficiency

Z Wang, J Ding, C Bai, Y Ding, X Ji, R Meng - Frontiers in Neurology, 2020 - frontiersin.org
Background: As an indispensable part of the cerebral venous system, the extracranial
cerebrospinal venous system is not fully recognized. This study aimed to analyze the clinical …

Fixing the jugular flow reduces ventricle volume and improves brain perfusion

P Zamboni, E Menegatti, C Cittanti, F Sisini… - Journal of Vascular …, 2016 - Elsevier
Objective Increased ventricle volume and brain hypoperfusion are linked to
neurodegeneration. We hypothesized that in patients with restricted jugular flow, surgical …

[HTML][HTML] Intra-and extracranial MR venography: Technical notes, clinical application, and imaging development

M Paoletti, G Germani, R De Icco, C Asteggiano… - Behavioural …, 2016 - hindawi.com
Scientific debate over chronic cerebrospinal venous insufficiency (CCSVI) has drawn
attention to venous system involvement in a series of pathologic brain conditions. In the last …