2023 update on sepsis and septic shock in adult patients: management in the emergency department

M Guarino, B Perna, AE Cesaro, M Maritati… - Journal of clinical …, 2023 - mdpi.com
Background: Sepsis/septic shock is a life-threatening and time-dependent condition that
requires timely management to reduce mortality. This review aims to update physicians with …

Antifungal drug resistance: an emergent health threat

A Vitiello, F Ferrara, M Boccellino, A Ponzo, C Cimmino… - Biomedicines, 2023 - mdpi.com
Fungal infections, named mycosis, can cause severe invasive and systemic diseases that
can even lead to death. In recent years, epidemiological data have recorded an increase in …

Advancements and challenges in antifungal therapeutic development

E Puumala, S Fallah, N Robbins… - Clinical Microbiology …, 2024 - Am Soc Microbiol
Over recent decades, the global burden of fungal disease has expanded dramatically. It is
estimated that fungal disease kills approximately 1.5 million individuals annually; however …

Invasive Candida infection: epidemiology, clinical and therapeutic aspects of an evolving disease and the role of rezafungin

A Oliva, FG De Rosa, M Mikulska, F Pea… - Expert Review of Anti …, 2023 - Taylor & Francis
ABSTRACT Introduction Invasive Candida Infections (ICIs) have undergone a series of
significant epidemiological, pathophysiological, and clinical changes during the last …

Pharmacokinetic and pharmacodynamic considerations for antifungal therapy optimisation in the treatment of intra-abdominal candidiasis

E Novy, C Roger, JA Roberts, MO Cotta - Critical Care, 2023 - Springer
Intra-abdominal candidiasis (IAC) is one of the most common of invasive candidiasis
observed in critically ill patients. It is associated with high mortality, with up to 50% of deaths …

Candida auris Outbreaks: Current Status and Future Perspectives

S De Gaetano, A Midiri, G Mancuso, MG Avola… - Microorganisms, 2024 - mdpi.com
Candida auris has been identified by the World Health Organization (WHO) as a critical
priority pathogen on its latest list of fungi. C. auris infections are reported in the bloodstream …

Emerging Challenges in Diagnosis and Treatment of Invasive Fungal Infections: Addressing the Impact of COVID-19 and New Pathogens

A Ahmadi, B Bashardoust, M Abdorahimi… - Current Fungal Infection …, 2023 - Springer
Abstract Purpose of Review Invasive fungal infections (IFIs) pose significant challenges in
healthcare settings, affecting a wide range of patient populations and often resulting in high …

Non-superficial Cutaneous Manifestations by Candida Species

G Figueroa-Ramos, SP Bermúdez-Rodríguez… - Current Fungal Infection …, 2024 - Springer
Abstract Purpose of Review To define adequate terminology regarding non-superficial or
deep cutaneous manifestations of infection by Candida, as well as to describe the most …

[PDF][PDF] Efficacy and safety of Lactobacillus plantarum P 17630 strain soft vaginal capsule in vaginal candidiasis: a randomized non-inferiority clinical trial.

C Bertarello, D Savio, L Morelli… - European Review for …, 2024 - europeanreview.org
OBJECTIVE: To investigate the non-inferiority of efficacy and tolerability of Lactobacillus
plantarum P 17630 soft vaginal cap-sules compared to the antifungal therapy with …

Management of invasive candidiasis: A focus on rezafungin, ibrexafungerp, and fosmanogepix

BA August, PB Kale‐Pradhan - Pharmacotherapy: The Journal …, 2024 - Wiley Online Library
Management of invasive fungal infections is challenging with growing antifungal resistance.
Broad antifungal use has resulted in greater intrinsic and acquired resistance among …