This review discusses the current state of the viral metabolism field and gaps in knowledge
that will be important for future studies to investigate. We discuss metabolic rewiring caused …

Human viral oncogenesis is a complex phenomenon and a major contributor to the global
cancer burden. Several recent findings revealed cellular and molecular pathways that …

Human T-cell lymphotropic virus type 1 (HTLV-1) is transmitted through a viral synapse and
enters target cells via interaction with the glucose transporter GLUT1. Here, we show that …

Heparan sulfate proteoglycans (HSPGs) are used by a number of viruses to facilitate entry
into host cells. For the retrovirus human T-cell leukemia virus type 1 (HTLV-1), it has recently …

The transcription factor NF-κB is critical for the induction of cancer, including adult T-cell
leukemia, which is linked to infection by human T-cell leukemia virus type 1 and the …

Human T-cell lymphotropic viruses type 1 and 2 are retroviruses that share the same routes
of transmission as HIV-1. Since these agents are prevalent simultaneously in different parts …

Infection by human T-cell lymphotropic virus type 1 (HTLV-1) occurs in lymphocytes, which
travel throughout the body, thus affecting several target organs and causing varied clinical …

Cancer cells increase their glucose uptake and glycolytic activity to meet the high energy
requirements of proliferation. Glucose transporters (GLUTs), which facilitate the transport of …

Primate tripartite motif 5α (TRIM5α) proteins mediate innate intracellular resistance to
retroviruses. In humans, TRIM5 is located in a paralogous cluster that includes TRIM6 …

Studies using adherent cell lines have shown that glucose transporter-1 (GLUT-1) can
function as a receptor for human T-cell leukemia virus type 1 (HTLV). In primary CD4+ T …