Lung cancer is one of the most common cancers and has a high mortality rate. Due to its
high incidence, the clinical management of the disease remains a major challenge. Several …

Cancer is a complex disease, and its treatment is a big challenge, with variable efficacy of
conventional anticancer drugs. A two-drug cocktail hybrid approach is a potential strategy in …

Caspases, a group of protease enzymes (cysteine proteases), exist as inactive zymogens in
the cells and execute apoptosis (programmed cell death). Caspase‐3, an executioner …

One of the leading global causes of death is cancer; even though several treatment methods
have improved survival rates, the incidence and fatality rates remain high. Naphthoquinones …

Mushrooms provide a reliable source of bioactive compounds and have numerous
nutritional values, which is one of the reasons why they are widely used for culinary …

Topoisomerases II are ubiquitous enzymes with significant genotoxic effects in many critical
DNA processes. Additionally, epidermal growth factor receptor (EGFR) plays pivotal role in …

Iridoids are glycosides found in plants, having inherent roles in defending them against
infection by viruses and microorganisms, and in the rapid repair of damaged areas. The …

Shikonin and its enantiomeric analogue, alkaninn, are prevailing natural lead compounds in
the drug discovery and development of anticancer agents. Despite having numerous …

Abstract A series of 11-substituted 9-hydroxy-3, 5, 10, 11-tetrahydro-2H-benzo [6, 7]
thiochromeno [2, 3-d][1, 3] thiazole-2, 5, 10-triones 3.1–3.13 were synthesized via hetero …

A visible-light-induced radical tandem cyclization/arylation between 2-amino-1, 4-
naphthoquinone and N-allyl-2-bromo-2, 2-difluoroacetamides has been developed without …