Triple-negative (TNBC) is the most lethal subtype of breast cancer owing to high
heterogeneity, aggressive nature, and lack of treatment options. Chemotherapy remains the …

Anthracyclines have been important and effective treatments against a number of cancers
since their discovery. However, their use in therapy has been complicated by severe side …

It is only recently that the full importance of nuclear factor-κB (NF-κB) signalling to cancer
development has been understood. Although much attention has focused on the upstream …

Triple-negative breast cancer (TNBC) is the most complex, aggressive and fatal subtype of
breast cancer. Owing to the lack of targeted therapy and heterogenic nature of TNBC …

Etoposide derives from podophyllotoxin, a toxin found in the American Mayapple. It was first
synthesized in 1966 and approved for cancer therapy in 1983 by the US Food and Drug …

Triple-negative breast cancer (TNBC) is associated with high recurrence rates, high
incidence of distant metastases, and poor overall survival (OS). Taxane and anthracycline …

Doxorubicin (DOX)-induced toxicity and resistance are major obstacles in chemotherapeutic
approaches. Despite effective in the treatment of numerous malignancies, some clinicians …

The application of immunotherapy for cancer treatment is rapidly becoming more
widespread. Immunotherapeutic agents are frequently combined with various types of …

In fish, stanniocalcin-1 (STC1) is a key endocrine factor that acts on gill, intestine and kidney
to regulate serum calcium and phosphate homeostasis. The recent identification and study …

Hepatocellular carcinoma, one of the most common solid tumors worldwide, is poorly
responsive to available chemotherapeutic approaches. While systemic chemotherapy is of …