Objective: Emotion recognition has been widely studied in Huntington disease (HD), but
only a few studies have investigated more complex social cognition and, when so …

Advances in high‐throughput technologies in genomics and imaging yield unprecedentedly
large numbers of prognostic biomarkers. To accommodate the scale of biomarkers and …

Abstract Study Objectives: Patients with Huntington's disease (HD) show a high prevalence
of sleep disorders that typically occur prior to the onset of motoric symptoms and …

Whether as a cause or a symptom, RNA transcription is recurrently altered in pathologic
conditions. This is also true for non-coding RNAs, with regulatory functions in a variety of …

Huntington's disease (HD) involves preferential and progressive degeneration of striatum
and other subcortical regions as well as regional cortical atrophy. It is caused by a CAG …

Huntington disease (HD) is caused by an abnormally expanded cytosine–adenine–guanine
(CAG) trinucleotide repeat in the HTT gene. Age and CAG-expansion number are related to …

The basal ganglia (BG) in the brain exhibit diverse functions for motor, cognition, and
emotion. Such BG functions could be made via competitive harmony between the two …

Purpose Huntington disease (HD) is an incurable terminal disease. Thus, end of life (EOL)
concerns are common in these individuals. A quantitative measure of EOL concerns in HD …

Helping neurons to compensate for proteotoxic stress and maintain function over time
(neuronal compensation) has therapeutic potential in aging and neurodegenerative …

Background: Huntington disease (HD) is associated with increased risk of suicide. Objective:
This study compares suicide ideation in HD to the general population, assesses factors …