OBJECTIVE: Acute myeloid leukemia (AML) develops de novo or secondarily to either
myelodysplastic syndrome (MDS) or anticancer treatment (therapy-related leukemia, TRL) …

Gene expression profiles of 10 children with acute lymphoblastic leukemia (ALL) were
detected using cDNA arrays. Total RNAs were isolated from peripheral blood leukocytes of …

In our previous work, lupeol was isolated from aerial parts of V. scorpioides and modified by
semisynthetic approach. The purpose of this study was to investigate the cytotoxicity of …

Receptors for granulocyte-macrophage colony-stimulating factor (GM-CSF) and interleukin-
3 (IL-3) share a common β subunit. We recently reported that GM-CSF acts in concert with …

To characterize the molecular mechanisms involved in the transition from the chronic phase
to blast crisis in chronic myelogenous leukemia (CML), gene expression profiles of leukemic …

Despite the lack of long-term survival data, the impressive results obtained with imatinib
mesylate (Gleevec®) therapy and the lack of serious adverse events have significantly …

Myelodysplastic syndrome (MDS) is an enigmatic disorder characterized by ineffective
hematopoiesis and dysplastic morphology of blood cells. The clinical course of MDS …

Considers the application of gene expression profiling in studies of hematological
malignancy. Implication of advances in gene microarray technology on the creation of …

Recent advances in gene microarray technology have facilitated global analyses of gene
expression profiles in normal and malignant immune cells. Great strides have been made in …

Objectives: Chronic myeloid leukaemia is caused by the expression of the p210 Bcr‐Abl
fusion protein which results from the Philadelphia translocation, t (9; 22). This oncogene has …