Fargesin inhibits melanin synthesis in murine malignant and immortalized melanocytes by regulating PKA/CREB and P38/MAPK signaling pathways

T Fu, B Chai, Y Shi, Y Dang, X Ye - Journal of Dermatological Science, 2019 - Elsevier
Background Fargesin is commonly used in the treatment of allergic rhinitis, inflammation,
sinusitis and headache. Objective The aim of the study is to investigate a new function of …

[HTML][HTML] Route of intracellular uptake and cytotoxicity of sesamol, sesamin, and sesamolin in human melanoma SK-MEL-2 cells

T Srisongkram, N Weerapreeyakul - Biomedicine & Pharmacotherapy, 2022 - Elsevier
The intracellular uptake concentration determines drug absorption, drug activity, and toxicity.
Sesamol, sesamin, and sesamolin are promising bioactive components from Sesame …

[HTML][HTML] Development of sesamol carbamate-L-phenylalanine prodrug targeting L-Type Amino Acid Transporter1 (LAT1) as a potential antiproliferative agent against …

T Srisongkram, K Bahrami, J Järvinen… - International Journal of …, 2022 - mdpi.com
Sesamol is a compound reported to have anti-melanogenesis and anti-melanoma actions.
Sesamol, however, has low intracellular drug concentration and fast excretion, which can …

UHPLC-QTOF-MS based metabolomics and biological activities of different parts of Eriobotrya japonica

L Zhang, FR Saber, G Rocchetti, G Zengin… - Food Research …, 2021 - Elsevier
Eriobotrya japonica, commonly known as loquat, has been used traditionally for the
treatment of different diseases. Herein, untargeted profiling based on ultra-high-performance …

[HTML][HTML] Hydrolyzed Conchiolin Protein (HCP) Extracted from Pearls Antagonizes both ET-1 and α-MSH for Skin Whitening

S Yang, Z Wang, Y Hu, K Zong, X Zhang, H Ke… - International Journal of …, 2023 - mdpi.com
Pearl powder is a famous traditional Chinese medicine that has a long history in treating
palpitations, insomnia, convulsions, epilepsy, ulcers, and skin lightining. Recently, several …

A comprehensive review on distribution, pharmacological properties, and mechanisms of action of sesamin

Y Zhang, F Liu, Y Lin, L Li, M Chen, L Ni - Journal of Chemistry, 2022 - Wiley Online Library
Sesamin is a kind of fat‐soluble lignan extracted from sesame seeds or other plants. It has
attracted more and more attention because of its extensive pharmacological activities. In this …

Biological properties of lemon basil seeds extract, legumes extract, sesame seeds extract and the inhibitory activity of the combination of lemon basil seeds extract …

N Buddhakala, T Sornkhwann, S Sansenya - Advances in Traditional …, 2023 - Springer
This research was conducted to evaluate the bioactive compounds content and biological
activity of legume extract (mung bean (MB), job's tears (JT), red kidney bean (RB) and black …

[HTML][HTML] Anti-tyrosinase and anti-melanogenic effects of piperine isolated from Piper nigrum on B16F10 mouse melanoma cells

P Khongkarat, P Sadangrit, S Puthong… - Heliyon, 2024 - cell.com
The essential function of melanin is to protect our skin against harmful environmental factors.
However, excessive melanin production can cause undesirable hyperpigmentation issues …

Synthesis and insecticidal activity of sulfonate derivatives of sesamol against Mythimna separata in vivo

ZP Che, JM Yang, XJ Shan, YE Tian… - Journal of Asian …, 2020 - Taylor & Francis
A series of sulfonate derivatives of sesamol were synthesized and evaluated for their
insecticidal activity against a crop-threatening agricultural pest, the pre-third-instar larvae of …

Analysis and classification of peanuts with fungal diseases based on real-time spectral processing

IA Lavrinenko, AO Donskikh, DA Minakov… - Food Additives & …, 2022 - Taylor & Francis
The study presents an approach to the analysis and classification of peanuts performed in
order to detect kernels with fungi diseases, ie kernels prone to contamination with …