Methods of in vitro toxicology

G Eisenbrand, B Pool-Zobel, V Baker, M Balls… - Food and chemical …, 2002 - Elsevier
In vitro methods are common and widely used for screening and ranking chemicals, and
have also been taken into account sporadically for risk assessment purposes in the case of …

Current state of the art and next generation of materials for a customized intraocular lens according to a patient-specific eye power

M Vacalebre, R Frison, C Corsaro, F Neri, A Santoro… - Polymers, 2023 - mdpi.com
Intraocular lenses (IOLs) are commonly implanted after surgical removal of a cataractous
lens. A variety of IOL materials are currently available, including collamer, hydrophobic …

Biocompatibility of intraocular lens materials

L Werner - Current opinion in Ophthalmology, 2008 - journals.lww.com
Intraocular lenses are being progressively implanted in much earlier stages of life (refractive
lens exchange, pediatric implantation) and are expected to remain in the intraocular …

Improvement of the surface biocompatibility of silicone intraocular lens by the plasma‐induced tethering of phospholipid moieties

K Yao, XD Huang, XJ Huang… - Journal of Biomedical …, 2006 - Wiley Online Library
To improve the surface biocompatibility of the silicone intraocular lens (IOL), 2‐
methacryloyloxyethyl phosphorylcholine (MPC) was tethered onto the IOL through air …

Bottom-up fabrication of zwitterionic polymer brushes on intraocular lens for improved biocompatibility

Y Han, X Xu, J Tang, C Shen, Q Lin… - International Journal of …, 2017 - Taylor & Francis
Intraocular lens (IOL) is an efficient implantable device commonly used for treating cataracts.
However, bioadhesion of bacteria or residual lens epithelial cells on the IOL surface after …

Adsorption/desorption phenomena on pure and Teflon® AF‐coated titania surfaces studied by dynamic contact angle analysis

F Rupp, D Axmann, C Ziegler… - Journal of Biomedical …, 2002 - Wiley Online Library
As a result of inflammatory processes, plaque formation on dental titanium implants often
leads to clinically pathogenic situations. This special biofilm formation on (bio) materials in …

Surface PEGylation of intraocular lens for PCO prevention: An in vivo evaluation

X Xu, JM Tang, YM Han, W Wang… - Journal of …, 2016 - journals.sagepub.com
Posterior capsular opacification (PCO) is a common complication in cataract surgery. The
development of PCO is attributed to the combination of adhesion, migration, proliferation …

The Boston Keratoprosthesis: comparing corneal epithelial cell compatibility with titanium and PMMA

JD Ament, SJ Spurr-Michaud, CH Dohlman, IK Gipson - Cornea, 2009 - journals.lww.com
Purpose: To determine in vitro whether titanium is superior in corneal cell compatibility to
standard polymethyl-methacrylate (PMMA) for the Boston Keratoprosthesis (KPro). Methods …

Development and evaluation of biocompatible films of polytetrafluoroethylene polymers holding lithium phthalocyanine crystals for their use in EPR oximetry

M Dinguizli, S Jeumont, N Beghein, J He… - Biosensors and …, 2006 - Elsevier
Electron paramagnetic resonance (EPR) oximetry is a powerful technology that allows the
monitoring of oxygenation in tissues. The measurement of tissue oxygenation can be …

Fouling in ocular devices: implications for drug delivery, bioactive surface immobilization, and biomaterial design

OJ Uwaezuoke, P Kumar, V Pillay… - Drug Delivery and …, 2021 - Springer
The last 30 years has seen a proliferation of research on protein-resistant biomaterials
targeted at designing bio-inert surfaces, which are prerequisite for optimal performance of …