Cell-type-specific in vivo delivery of genome editing molecules is the next breakthrough that
will drive biological discovery and transform the field of cell and gene therapy. Here, we …

Gene therapy using adeno-associated viral (AAV) vectors is a promising therapeutic strategy
for multiple inherited diseases. Following intravenous injection, AAV vectors carrying a copy …

Cell therapies derived from induced pluripotent stem cells (iPSCs) offer a promising avenue
in the field of regenerative medicine due to iPSCs' expandability, immune compatibility, and …

Background: Sarcopenia is an aging-related degeneration of muscle mass and strength.
Small-molecule inhibitor SW033291 has been shown to attenuate muscle atrophy. Targeted …

A recent study published in Cell by the Millay lab reports on an elegant strategy to expand
the repertoire of lentiviral (LV) vectors from being the main delivery tool for ex vivo gene …

Viruses and multinucleated cells rely on fusogens to facilitate the fusion of their membranes.
In this issue of Cell, Millay and colleagues demonstrate that replacing viral fusogens with …

Myocyte fusion is a pivotal process in the development and regeneration of skeletal muscle.
Failure during fusion can lead to a range of developmental as well as pathological …

El 25 de abril de 1953 se publicaba en la prestigiosa revista Nature un artículo denominado
“Estructura molecular de los ácidos nucleicos; una estructura para el ácido …