Treatment outcomes in anaplastic thyroid cancer

KL Corrigan, H Williamson… - Journal of Thyroid …, 2019 - Wiley Online Library
Background. Anaplastic thyroid cancer (ATC) is rare, accounting for 1‐2% of thyroid
malignancies. Median survival is only 3‐10 months, and the optimal therapeutic approach …

[PDF][PDF] Anaplastic thyroid cancer: ultrasonographic findings and the role of ultrasonography-guided fine needle aspiration biopsy

HJ Suh, HJ Moon, JY Kwak, JS Choi… - Yonsei medical …, 2013 - synapse.koreamed.org
Purpose To investigate the ultrasonographic (US) features of anaplastic thyroid cancer
(ATC) and the diagnostic performance of US-guided fine needle aspiration biopsy (FNAB) …

The heat shock protein 90-binding geldanamycin inhibits cancer cell proliferation, down-regulates oncoproteins, and inhibits epidermal growth factor-induced invasion …

JW Park, MW Yeh, MG Wong, M Lobo… - The Journal of …, 2003 - academic.oup.com
Heat shock protein 90 (HSP90) serves as a chaperone protein and plays a critical role in
tumor cell growth and/or survival. Geldanamycin, a specific inhibitor of HSP90, is cytotoxic to …

Pathology and cytologic features of thyroid neoplasms

KM Malloy, MF Cunnane - Surgical oncology clinics of North America, 2008 - Elsevier
Most thyroid neoplasms arise from follicular cells and are well differentiated. Anaplastic and
poorly differentiated carcinomas are rare and have a high mortality. Five percent of tumors …

Evaluation of the sensitivity to chemotherapeutics or thiazolidinediones of primary anaplastic thyroid cancer cells obtained by fine-needle aspiration

A Antonelli, SM Ferrari, P Fallahi, P Berti… - European Journal of …, 2008 - academic.oup.com
Objective Anaplastic thyroid cancer (ATC) is often unoperable and chemotherapy and
radiotherapy are the main treatments. Until now 'primary ATC cell cultures'(ANA) have been …

Anaplastic thyroid cancer: outcome and the mutation/expression profiles of potential targets

H Wu, Y Sun, H Ye, S Yang, SL Lee… - Pathology & Oncology …, 2015 - Springer
Abstracts Anaplastic thyroid cancer (ATC) is a rare but aggressive malignancy of the thyroid.
No effective treatment modalities are currently available. Targeted therapy against protein …

Anaplastic thyroid carcinoma in Denmark 1996–2012: A national prospective study of 219 patients

GB Hvilsom, SC Londero, CH Hahn, S Schytte… - Cancer …, 2018 - Elsevier
Background Anaplastic thyroid carcinoma (ATC) is the least common but most malignant
thyroid cancer. We aimed to examine the characteristics as well as evaluate the incidence …

Anaplastic thyroid cancer: the addition of systemic chemotherapy to radiotherapy led to an observed improvement in survival—a single centre experience and review …

NM Lowe, S Loughran, NJ Slevin… - The Scientific World …, 2014 - Wiley Online Library
Introduction. Anaplastic thyroid carcinoma (ATC) is rare yet accounts for up to 50% of all
thyroid cancer deaths. This study reviews outcomes of patients with confirmed ATC referred …

[HTML][HTML] Hypofractionated radiotherapy for anaplastic thyroid carcinoma: 15 years of experience in a single institution

N Takahashi, H Matsushita, R Umezawa… - European Thyroid …, 2019 - etj.bioscientifica.com
Background: Anaplastic thyroid carcinoma (ATC) is a rare cancer and has a poor prognosis.
Several radiation protocols have been reported, but the results were not satisfactory …

Super‐radical surgery for anaplastic thyroid carcinoma: A large cohort study using the anaplastic thyroid carcinoma research consortium of Japan database

I Sugitani, Y Hasegawa, M Sugasawa, M Tori… - Head & …, 2014 - Wiley Online Library
Background The consequences of super‐radical resection in patients with anaplastic thyroid
carcinoma (ATC) have not been fully investigated. Methods This retrospective study used …