Targeting oxidative stress as a preventive and therapeutic approach for cardiovascular disease
Q Yan, S Liu, Y Sun, C Chen, S Yang, M Lin… - Journal of Translational …, 2023 - Springer
Cardiovascular diseases (CVDs) continue to exert a significant impact on global mortality
rates, encompassing conditions like pulmonary arterial hypertension (PAH), atherosclerosis …
rates, encompassing conditions like pulmonary arterial hypertension (PAH), atherosclerosis …
Mitochondrial homeostasis in VSMCs as a central hub in vascular remodeling
Y Xia, X Zhang, P An, J Luo, Y Luo - International journal of molecular …, 2023 - mdpi.com
Vascular remodeling is a common pathological hallmark of many cardiovascular diseases.
Vascular smooth muscle cells (VSMCs) are the predominant cell type lining the tunica media …
Vascular smooth muscle cells (VSMCs) are the predominant cell type lining the tunica media …
Accelerated discovery of superoxide-dismutase nanozymes via high-throughput computational screening
The activity of nanomaterials (NMs) in catalytically scavenging superoxide anions mimics
that of superoxide dismutase (SOD). Although dozens of NMs have been demonstrated to …
that of superoxide dismutase (SOD). Although dozens of NMs have been demonstrated to …
Uremic toxins and frailty in patients with chronic kidney disease: a molecular insight
The accumulation of uremic toxins (UTs) is a prototypical manifestation of uremic milieu that
follows renal function decline (chronic kidney disease, CKD). Frailty as a potential outcome …
follows renal function decline (chronic kidney disease, CKD). Frailty as a potential outcome …
NIPSNAP1 directs dual mechanisms to restrain senescence in cancer cells
E Gao, X Sun, RF Thorne, XD Zhang, J Li… - Journal of Translational …, 2023 - Springer
Background Although the executive pathways of senescence are known, the underlying
control mechanisms are diverse and not fully understood, particularly how cancer cells avoid …
control mechanisms are diverse and not fully understood, particularly how cancer cells avoid …
[HTML][HTML] Epigenetically regulated inflammation in vascular senescence and renal progression of chronic kidney disease
Chronic kidney disease (CKD) and its complications, including vascular senescence and
progressive renal fibrosis, are associated with inflammation. Vascular senescence, in …
progressive renal fibrosis, are associated with inflammation. Vascular senescence, in …
Gender-related differences in chronic kidney disease-associated vascular calcification risk and potential risk mediators: a scoping review
Vascular calcification (VC) involves the deposition of calcium apatite in vascular intima or
media. Individuals of advanced age, having diabetes mellitus or chronic kidney disease …
media. Individuals of advanced age, having diabetes mellitus or chronic kidney disease …
Diabetes mellitus to accelerated atherosclerosis: Shared cellular and molecular mechanisms in glucose and lipid metabolism
N Zhao, X Yu, X Zhu, Y Song, F Gao, B Yu… - Journal of Cardiovascular …, 2024 - Springer
Diabetes is one of the critical independent risk factors for the progression of cardiovascular
disease, and the underlying mechanism regarding this association remains poorly …
disease, and the underlying mechanism regarding this association remains poorly …
Phenotypic plasticity of vascular smooth muscle cells in vascular calcification: Role of mitochondria
YZ Liu, ZX Li, LL Zhang, D Wang… - Frontiers in Cardiovascular …, 2022 - frontiersin.org
Vascular calcification (VC) is an important hallmark of cardiovascular disease, the osteo-
/chondrocyte phenotype differentiation of vascular smooth muscle cells (VSMCs) is the main …
/chondrocyte phenotype differentiation of vascular smooth muscle cells (VSMCs) is the main …
Construction of the circRNA‐miRNA‐mRNA Regulatory Network of an Abdominal Aortic Aneurysm to Explore Its Potential Pathogenesis
H Zhang, C Bian, S Tu, F Yin, P Guo, J Zhang… - Disease …, 2021 - Wiley Online Library
Background. Abdominal aortic aneurysm (AAA) is a progressive cardiovascular disease,
which is a permanent and localized dilatation of the abdominal aorta with potentially fatal …
which is a permanent and localized dilatation of the abdominal aorta with potentially fatal …