Tight coordination between transcription and translation is crucial to maintaining the integrity
of gene expression in bacteria, yet how bacteria manage to coordinate these two processes …

If biomanufacturing can become a sustainable route for producing chemicals, it will provide
a critical step in reducing greenhouse gas emissions to fight climate change. However …

Antibiotics constitute one of the cornerstones of modern medicine. However, individuals may
succumb to a bacterial infection if a pathogen survives exposure to antibiotics. The ability of …

Over the past two decades, synthetic biological systems have revolutionized the study of
cellular physiology. The ability to site‐specifically incorporate biologically relevant non …

Effective coordination of cellular processes is critical to ensure the competitive growth of
microbial organisms. Pivotal to this coordination is the appropriate partitioning of cellular …

Antibiotic tolerance—the ability of bacteria to survive for an extended time in the presence of
bactericidal antibiotics—is an understudied contributor to antibiotic treatment failure. Herein …

The inherent stochasticity of metabolism raises a critical question for understanding
homeostasis: are cellular processes regulated in response to internal fluctuations? Here, we …

Growth and survival are key determinants of bacterial fitness. However, how resource
allocation of bacteria could reconcile these two traits to maximize fitness remains poorly …

Growth and division are central to cell size. Bacteria achieve size homeostasis by dividing
when growth has added a constant size since birth, termed the adder principle, by unknown …

Abstract Guanosine 3′, 5′-bis (pyrophosphate)(ppGpp) functions as a second messenger
in bacteria to adjust their physiology in response to environmental changes. In recent years …