Host-circuit coupling: toward a new framework for genetic circuit design
CHU Pan, ZHU Jingwen… - Synthetic Biology …, 2021 - synbioj.cip.com.cn
With the rapid development of synthetic biology and increasing demand for complicated
artificial life systems, increased complexity and scale have been observed in the design of …
artificial life systems, increased complexity and scale have been observed in the design of …
[图书][B] Predicting Antibiotic Effectiveness Across the Range of Bacterial Diversity
S Mathur - 2021 - search.proquest.com
How antibiotic efficacy varies with bacterial species is of basic and applied importance,
including understanding of microbial dynamics in clinical and ecological contexts. Cellular …
including understanding of microbial dynamics in clinical and ecological contexts. Cellular …
Novel insights into amino-acid catabolism and the characterisation of a ncRNA regulating BCAA biosynthesis in bacteria
S Knorr - 2020 - kops.uni-konstanz.de
Amino acid metabolism is not only of interest because of its impact on protein biosynthesis
as the motor for catalytic processes in the cell, but also catabolism of amino acids …
as the motor for catalytic processes in the cell, but also catabolism of amino acids …
Fusion of the N-terminal 119 amino acids with the RelA-CTD renders its growth inhibitory effects ppGpp-dependent
K Tailor, P Sagar, K Dave, J Pohnerkar - bioRxiv, 2021 - biorxiv.org
The guanosine nucleotide derivatives ppGpp and pppGpp, are central to the remarkable
capacity of bacteria to adapt to fluctuating environment and metabolic perturbations. These …
capacity of bacteria to adapt to fluctuating environment and metabolic perturbations. These …
Predicting the fitness costs of complex mutations
P Yubero, JF Poyatos - bioRxiv, 2021 - biorxiv.org
The fitness cost of complex pleiotropic mutations is generally difficult to assess. On the one
hand, it is necessary to identify which molecular properties are directly altered by the …
hand, it is necessary to identify which molecular properties are directly altered by the …
Fusion of the N-terminal 119 amino acids of RelA with the CTD domain render growth inhibitory effects of the latter,(p) ppGpp-dependent
K Tailor, P Sagar, K Dave, J Pohnerkar - Molecular Genetics and …, 2022 - Springer
The guanosine nucleotide derivatives ppGpp and pppGpp are central to the remarkable
capacity of bacteria to adapt to fluctuating environments and metabolic perturbations. They …
capacity of bacteria to adapt to fluctuating environments and metabolic perturbations. They …
Stringent Response Governs the Virulence and Oxidative Stress Resistance of Francisella tularensis
K King - 2019 - search.proquest.com
Francisella tularensis (F. tularensis) is a Gram-negative facultative intracellular human
pathogen responsible for causing tularemia. It is also classified as a Category A agent by the …
pathogen responsible for causing tularemia. It is also classified as a Category A agent by the …
Characterizing the landscape of aminoacyl-tRNA synthetase protein production in Bacillus subtilis
DJ Parker - 2020 - dspace.mit.edu
In Chapter I, I outline the conceptual questions explored in this thesis, review the current
understandings of bacterial translation and aaRS function, and note the various regulatory …
understandings of bacterial translation and aaRS function, and note the various regulatory …