Evolution of Streptococcus pneumoniae and Its Close Commensal Relatives

M Kilian, K Poulsen, T Blomqvist, LS Håvarstein… - PloS one, 2008 - journals.plos.org
Streptococcus pneumoniae is a member of the Mitis group of streptococci which, according
to 16S rRNA-sequence based phylogenetic reconstruction, includes 12 species. While other …

The Versatility of Opportunistic Infections Caused by Gemella Isolates Is Supported by the Carriage of Virulence Factors From Multiple Origins

E García López, AJ Martín-Galiano - Frontiers in microbiology, 2020 - frontiersin.org
The molecular basis of the pathogenesis of the opportunistic invasive infections caused by
isolates of the Gemella genus remains largely unknown. Moreover, inconsistencies in the …

Site-specialization of human oral Gemella species

J Torres-Morales, JL Mark Welch… - Journal of Oral …, 2023 - Taylor & Francis
Gemella species are core members of the human oral microbiome in healthy subjects and
are regarded as commensals, although they can cause opportunistic infections. Our …

Occurrence and evolution of the paralogous zinc metalloproteases IgA1 protease, ZmpB, ZmpC, and ZmpD in Streptococcus pneumoniae and related commensal …

M Bek-Thomsen, K Poulsen, M Kilian - MBio, 2012 - Am Soc Microbiol
The distribution, genome location, and evolution of the four paralogous zinc
metalloproteases, IgA1 protease, ZmpB, ZmpC, and ZmpD, in Streptococcus pneumoniae …

IgA-specific proteins of pathogenic bacteria

TN Kazeeva, AB Shevelev - Biochemistry (Moscow), 2009 - Springer
Data on structure and specificity of bacterial IgA receptors (IgA-binding M-like proteins Arp4
and Sir22 from hemolytic streptococci of serogroup A, β-antigen from hemolytic streptococci …

[HTML][HTML] Gemella endocarditis

H Rabah, K El Gharib, M Assaad, A Kassem… - IDCases, 2022 - Elsevier
We herein present the case presenting to our facility complaining of a fever of two months
duration, who underwent dental procedure. Patient was diagnosed with infective …

Comparative genomics and evolution of the amylase-binding proteins of oral streptococci

EM Haase, Y Kou, A Sabharwal, YC Liao, T Lan… - BMC microbiology, 2017 - Springer
Background Successful commensal bacteria have evolved to maintain colonization in
challenging environments. The oral viridans streptococci are pioneer colonizers of dental …

A substrate-induced gating mechanism is conserved among Gram-positive IgA1 metalloproteases

JS Redzic, J Rahkola, N Tran, T Holyoak, E Lee… - Communications …, 2022 - nature.com
The mucosal adaptive immune response is dependent on the production of IgA antibodies
and particularly IgA1, yet opportunistic bacteria have evolved mechanisms to specifically …

Gemella morbillorum infective endocarditis: A case report and literature review

X Cao, L Yuan - Open Life Sciences, 2023 - degruyter.com
Infective endocarditis (IE) caused by Gemella morbillorum is rare. Consequently, little is
known about the natural course of endocarditis caused by this pathogen. This report …

Identification of a human immunodominant B-cell epitope within the immunoglobulin A1 protease of Streptococcus pneumoniae

F De Paolis, E Beghetto, A Spadoni, F Montagnani… - BMC microbiology, 2007 - Springer
Abstract Background The IgA1 protease of Streptococcus pneumoniae is a proteolytic
enzyme that specifically cleaves the hinge regions of human IgA1, which dominates most …