Transportation noise is a ubiquitous urban exposure. In 2018, the World Health Organization
concluded that chronic exposure to road traffic noise is a risk factor for ischemic heart …

Activation of signal transducer and activator of transcription 3 (STAT3) has been identified as
a key cardioprotective signal not only in animal studies but also in humans—in animals …

Numerous physiological and pathological roles have been attributed to the formation of
mitochondrial reactive oxygen species (ROS). However, the individual contribution of …

Mitochondrial function is critical to myocardial ischemia-reperfusion injury and
cardioprotection. The measurement of mitochondrial function in isolated mitochondria …

The present review summarizes the beneficial and detrimental roles of reactive oxygen
species in myocardial ischemia/reperfusion injury and cardioprotection. In the first part, the …

Abstract Background: Catalpol (CAT), a naturally occurring iridoid glycoside sourced from
the root of Rehmannia glutinosa, affects mitochondrial metabolic functions. However, the …

Increased mitochondrial reactive oxygen species (ROS) formation is important for the
development of right ventricular (RV) hypertrophy (RVH) and failure (RVF) during pulmonary …

Serotonin effects on cardiac hypertrophy, senescence, and failure are dependent either on
activation of specific receptors or serotonin uptake and serotonin degradation by …

Permeability transition pore (PTP) opening dissipates ion and electron gradients across the
internal mitochondrial membrane (IMM), including excess Ca2+ in the mitochondrial matrix …

慢性心力衰竭是多种心血管疾病进行性加重的终末阶段, 衰老作为心力衰竭的独立危险因素会
造成患病率升高. 心室重构是慢性心力衰竭的主要病理生理基础, 除炎性反应相关细胞因子活性 …