Antigen Capture and Immune Modulation by Bacterial Outer Membrane Vesicles as In Situ Vaccine for Cancer Immunotherapy Post‐Photothermal Therapy

Y Li, K Zhang, Y Wu, Y Yue, K Cheng, Q Feng, X Ma… - Small, 2022 - Wiley Online Library
Tumor antigens released from tumor cells after local photothermal therapy (PTT) can
activate the tumor‐specific immune responses, which are critical for eliminating the residual …

The reparative roles of IL-33

JB Saba, HR Turnquist - Transplantation, 2023 - journals.lww.com
When discovered in the early 2000s, interleukin-33 (IL-33) was characterized as a potent
driver of type 2 immunity and implicated in parasite clearance, as well as asthma, allergy …

Multifunctional hydrogel modulates the immune microenvironment to improve allogeneic spinal cord tissue survival for complete spinal cord injury repair

X Gao, Z You, Y Li, X Kang, W Yang, H Wang, T Zhang… - Acta biomaterialia, 2023 - Elsevier
Transplantation of allogeneic adult spinal cord tissues (aSCTs) to replace the injured spinal
cord, serves as a promising strategy in complete spinal cord injury (SCI) repair. However, in …

The Role of Mesenchymal Stem/Stromal Cells Secretome in Macrophage Polarization: Perspectives on Treating Inflammatory Diseases

D Ti, J Yi, H Chen, H Hao, C Shi - Current Stem Cell Research …, 2024 - ingentaconnect.com
Mesenchymal stem/stromal cells (MSCs) have exhibited potential for treating multiple
inflammation-related diseases (IRDs) due to their easy acquisition, unique …

Single-cell analysis of graft-infiltrating host cells identifies caspase-1 as a potential therapeutic target for heart transplant rejection

Z Wu, J Liang, S Zhu, N Liu, M Zhao, F Xiao… - Frontiers in …, 2023 - frontiersin.org
Aims Understanding the cellular mechanisms underlying early allograft rejection is crucial
for the development of effective immunosuppressant strategies. This study aims to …

Hepatocyte-derived extracellular vesicles miR-122-5p promotes hepatic ischemia reperfusion injury by regulating Kupffer cell polarization

L Liu, F Xiao, J Sun, Q Wang, A Wang, F Zhang… - International …, 2023 - Elsevier
Ischemia reperfusion injury remains a major barrier to liver transplantation, especially using
grafts from donation after circulatory death, and it is also a pressing issue to be solved in …

Induction of Foxp3 and activation of Tregs by HSP gp96 for treatment of autoimmune diseases

Y Xu, E Liu, X Xie, J Wang, H Zheng, Y Ju, L Chen, C Li… - Iscience, 2021 - cell.com
Upregulation and stabilization of Foxp3 expression in Tregs are essential for regulating Treg
function and immune homeostasis. In this study, gp96 immunization showed obvious …

[HTML][HTML] Macrophage-inducible C-type lectin activates B cells to promote T cell reconstitution in heart allograft recipients

S Hasgur, Y Yamamoto, R Fan, M Nicosia… - American Journal of …, 2022 - Elsevier
Diminishing homeostatic proliferation of memory T cells is essential for improving the
efficacy of lymphoablation in transplant recipients. Our previous studies in a mouse heart …

Examination of the role of necroptotic damage-associated molecular patterns in tissue fibrosis

X Liu, F Lu, X Chen - Frontiers in Immunology, 2022 - frontiersin.org
Fibrosis is defined as the abnormal and excessive deposition of extracellular matrix (ECM)
components, which leads to tissue or organ dysfunction and failure. However, the …

Pharmacological insights and role of bufalin (bufadienolides) in inflammation modulation: a narrative review

G Kaur, S Devi, A Sharma, P Sood - Inflammopharmacology, 2024 - Springer
Bufadienolides, specifically bufalin, have garnered attention for their potential therapeutic
application in modulating inflammatory pathways. Bufalin is derived from toad venom and …