[HTML][HTML] Microbiome dysbiosis: a pathological mechanism at the intersection of obesity and glaucoma

S Pezzino, M Sofia, LP Greco, G Litrico… - International Journal of …, 2023 - mdpi.com
The rate at which obesity is becoming an epidemic in many countries is alarming. Obese
individuals have a high risk of developing elevated intraocular pressure and glaucoma …

The metabolic syndrome, a human disease

M Alemany - International journal of molecular sciences, 2024 - mdpi.com
This review focuses on the question of metabolic syndrome (MS) being a complex, but
essentially monophyletic, galaxy of associated diseases/disorders, or just a syndrome of …

[HTML][HTML] Impact of systemic comorbidities on ocular hypertension and open-angle glaucoma, in a population from Spain and Portugal

C Garcia-Villanueva, E Milla, JM Bolarin… - Journal of Clinical …, 2022 - mdpi.com
Open-angle glaucoma (OAG), the most prevalent clinical type of glaucoma, is still the main
cause of irreversible blindness worldwide. OAG is a neurodegenerative illness for which the …

[HTML][HTML] Phenotypic and genetic links between body fat measurements and primary open-angle glaucoma

SS Rong, X Yu - International Journal of Molecular Sciences, 2023 - mdpi.com
The phenotypic and genetic links between body fat phenotypes and primary open-angle
glaucoma (POAG) are unclear. We conducted a meta-analysis of relevant longitudinal …

Association between Glucagon-like Peptide-1 Receptor Agonists and the Risk of Glaucoma in Individuals with Type 2 Diabetes

S Niazi, F Gnesin, AS Thein, JR Andreasen, A Horwitz… - Ophthalmology, 2024 - Elsevier
Purpose To examine the association between glucagon-like peptide-1 receptor agonist
(GLP-1RA) use and the development of glaucoma in individuals with type 2 diabetes …

Shedding light on eye disease in obesity: A review

S Lam, J Lindsey, BG Carranza Leon… - Clinical …, 2024 - Wiley Online Library
Obesity is known to be associated with numerous ocular manifestations, including but not
limited to, diabetic retinopathy (DR), age‐related macular degeneration (AMD), cataracts …

[HTML][HTML] Differences in factors Associated with Glaucoma progression with lower normal intraocular pressure in Superior and Inferior halves of the Optic nerve head

R Asaoka, R Sakata, T Yoshitomi… - … Vision Science & …, 2023 - tvst.arvojournals.org
Purpose: The purpose of this study was to investigate risk factors for progression in the
superior and inferior hemi-visual fields (hemi-VFs) and the corresponding hemi-disc/retinas …

[HTML][HTML] BMI and plasma lipid levels with risk of proliferative diabetic retinopathy: a univariable and multivariable Mendelian randomization study

Y Shu, Q Zhou, Y Shao, H Lin, S Qu, W Han, X Lv… - Frontiers in …, 2023 - frontiersin.org
Background The study aimed to determine whether a causal effect exists between body
mass index (BMI) or plasma lipid levels and proliferative diabetic retinopathy (PDR) risk in …

[HTML][HTML] Causal factors in primary open angle glaucoma: a phenome-wide Mendelian randomisation study

TH Julian, Z Girach, E Sanderson, H Guo, J Yu… - Scientific Reports, 2023 - nature.com
Primary open angle glaucoma (POAG) is a chronic, adult-onset optic neuropathy associated
with characteristic optic disc and/or visual field changes. With a view to identifying modifiable …

Causality of Diabetic Nephropathy and Age-Related Macular Degeneration: A Mendelian Randomization Study

X Chen, L Chen, Y Lin, G Li - Gene, 2023 - Elsevier
Purpose Age-related macular degeneration (AMD) currently stands as the leading cause of
irreversible vision loss in the present era. The primary objective of this study was to …