[HTML][HTML] Therapeutic targets for cardiac fibrosis: from old school to next-gen
Cardiovascular diseases remain the leading cause of death worldwide, with pathological
fibrotic remodeling mediated by activated cardiac myofibroblasts representing a unifying …
fibrotic remodeling mediated by activated cardiac myofibroblasts representing a unifying …
Is cardiac diastolic dysfunction a part of post-menopausal syndrome?
PZ Maslov, JK Kim, E Argulian, A Ahmadi, N Narula… - JACC: Heart Failure, 2019 - jacc.org
Post-menopausal women exhibit an exponential increase in the incidence of heart failure
with preserved ejection fraction compared with men of the same age, which indicates a …
with preserved ejection fraction compared with men of the same age, which indicates a …
[HTML][HTML] Protective effects of Salidroside on cardiac function in mice with myocardial infarction
P Chen, J Liu, H Ruan, M Zhang, P Wu, D Yimei… - Scientific reports, 2019 - nature.com
Salidroside (SAL) is the major ingredient of Rhodiola rosea, and has been traditionally used
in Chinese medicine for decades. Numerous studies have demonstrated the protective …
in Chinese medicine for decades. Numerous studies have demonstrated the protective …
[HTML][HTML] MiR-320 regulates cardiomyocyte apoptosis induced by ischemia–reperfusion injury by targeting AKIP1
ZQ Tian, H Jiang, ZB Lu - Cellular & molecular biology letters, 2018 - Springer
Background MicroRNAs play important roles in regulation of the cardiovascular system. The
purpose of this study was to investigate microRNA-320 (miR-320) expression in myocardial …
purpose of this study was to investigate microRNA-320 (miR-320) expression in myocardial …
[HTML][HTML] Sodium-glucose cotransporter 2 inhibitors' mechanisms of action in heart failure
PG Rotkvić, MC Berković, N Bulj, L Rotkvić… - World journal of …, 2020 - ncbi.nlm.nih.gov
Three major cardiovascular outcome trials (CVOTs) with a new class of antidiabetic drugs-
sodium-glucose cotransporter 2 (SGLT2) inhibitors (EMPA-REG OUTCOME trial with …
sodium-glucose cotransporter 2 (SGLT2) inhibitors (EMPA-REG OUTCOME trial with …
[HTML][HTML] Lycopene attenuates inflammation and apoptosis in post‑myocardial infarction remodeling by inhibiting the nuclear factor‑κB signaling pathway
QIN He, WEI Zhou, C Xiong… - Molecular Medicine …, 2015 - spandidos-publications.com
Inflammatory response and cardiomyocyte apoptosis are important processes in ventricular
remodeling post‑myocardial infarction (MI) and may form the basic mechanisms in the …
remodeling post‑myocardial infarction (MI) and may form the basic mechanisms in the …
Long non-coding RNA GAS5 reduces cardiomyocyte apoptosis induced by MI through sema3a
S Hao, X Liu, X Sui, Y Pei, Z Liang, N Zhou - International journal of …, 2018 - Elsevier
Objective To investigate the role of GAS5 on cardiomyocyte apoptosis. Methods Myocardial
infarction (MI) model was established by the left-anterior descending coronary artery …
infarction (MI) model was established by the left-anterior descending coronary artery …
Stilbenoid pterostilbene complexed with cyclodextrin preserves left ventricular function after myocardial infarction in rats: possible involvement of thiol proteins and …
D Lacerda, V Ortiz, P Türck… - Free radical …, 2018 - Taylor & Francis
Oxidative stress alters signalling pathways for survival and cell death favouring the adverse
remodelling of postmyocardial remnant cardiomyocytes, promoting functional impairment …
remodelling of postmyocardial remnant cardiomyocytes, promoting functional impairment …
[HTML][HTML] Shengmai Injection Suppresses Angiotensin II-Induced Cardiomyocyte Hypertrophy and Apoptosis via Activation of the AMPK Signaling Pathway Through …
Y Li, X Ruan, X Xu, C Li, T Qiang, H Zhou… - Frontiers in …, 2019 - frontiersin.org
Shengmai injection (SMI), a traditional Chinese herbal medicine extracted from Panax
ginseng CA Mey., Ophiopogon japonicus (Thunb.) Ker Gawl., and Schisandra chinensis …
ginseng CA Mey., Ophiopogon japonicus (Thunb.) Ker Gawl., and Schisandra chinensis …
Ellagic acid promotes ventricular remodeling after acute myocardial infarction by up-regulating miR-140-3p
D Wei, C Lin, Y Huang, L Wu, M Huang - Biomedicine & Pharmacotherapy, 2017 - Elsevier
In the paper, we observed the effect of ellagic acid (EA) on myocardial morphology and
cardiac function and explored the mechanism of miR-140-3p-mediated EA in ventricular …
cardiac function and explored the mechanism of miR-140-3p-mediated EA in ventricular …