Free fatty acids induce bile acids overproduction and oxidative damage of bovine hepatocytes via inhibiting FXR/SHP signaling

Z Fang, Z Zhou, L Ju, Q Shao, Y Xu, Y Song… - The Journal of Steroid …, 2024 - Elsevier
Hepatic oxidative injury induced by free fatty acids (FFA) and metabolic disorders of bile
acids (BA) increase the risk of metabolic diseases in dairy cows during perinatal period …

Treatment of animals with fatty liver disease using a drug based on the seeds of Silybum marianum

V Vlizlo, O Prystupa, L Slivinska, B Gutyj… - Regulatory …, 2023 - medicine.dp.ua
Medicinal plants are a source of various therapeutic preparations. Therefore, the aim of our
work was to prepare a liposomal drug from extract from the seeds of Silybum marianum (L.) …

[HTML][HTML] Effects of dietary palmitic acid and oleic acid ratio on milk production, nutrient digestibility, blood metabolites and milk fatty acids profile of lactating dairy cows

L Hu, Y Shen, H Zhang, N Ma, Y Li, H Xu, M Wang… - Journal of Dairy …, 2024 - Elsevier
Adequate energy supply is a crucial factor for maintaining the production performance in
early lactating cows. Adding fatty acids to diets can improve energy supply, while the effect …

Hepatic metabolism of grazing cows of two Holstein strains under two feeding strategies with different levels of pasture inclusion

M García-Roche, D Talmón, G Cañibe, AL Astessiano… - Plos one, 2023 - journals.plos.org
The objective of the study was to characterize adaptations of hepatic metabolism of dairy
cows of two Holstein strains with varying proportions of grazing in the feeding strategy …

Serum macroelements and microelements levels in periparturient dairy cows in relation to fatty liver diseases

KX Zhang, K Li, ZH Li, XC Liu, MM Li, S Jiang… - BMC Veterinary …, 2024 - Springer
Background Fatty liver in dairy cows is a common metabolic disease defined by triglyceride
(TG) buildup in the hepatocyte. Clinical diagnosis of fatty liver is usually done by liver biopsy …

Transcriptomic analysis reveals pharmacological mechanisms mediating efficacy of Yangyinghuoxue Decoction in CCl4-induced hepatic fibrosis in rats

Y Bai, S Liang, Y Zhou, B Zhou - Frontiers in Pharmacology, 2024 - frontiersin.org
Background and purpose As a traditional Chinese medicine formula, Yangyinghuoxue
Decoction (YYHXD) is used clinically for therapy of hepatic fibrosis. The pharmacological …

Effect of dietary Glycyrrhiza polysaccharides on growth performance, hepatic antioxidant capacity and anti-inflammatory capacity of broiler chickens

X Ji, H Hou, X Wang, Y Qiu, Y Ma, S Wang… - Research in Veterinary …, 2024 - Elsevier
The primary aim of this study was to investigate the impact of varying levels of dietary
Glycyrrhiza polysaccharides (GPS) on the health status of broiler chickens. A total of 288 1 …

[HTML][HTML] Comparative quantitation of liver-type fatty acid-binding protein localizations in liver injury and non-pathological liver tissue in dogs

J Arunorat, N Chusakulwong, N Sakunasing… - Veterinary …, 2024 - ncbi.nlm.nih.gov
Materials and Methods: Liver tissue samples were collected from dog biopsy specimens at
the Veterinary Diagnostic Laboratory at the Faculty of Veterinary Medicine, Chiang Mai …

绿原酸对高游离脂肪酸处理犊牛肝细胞胆固醇和胆汁酸代谢的影响

田艳, 刘佳晨, 王爽, 范文文, 常雅奇, 杨天娇, 张泽鑫… - 中国畜牧兽医, 2024 - chvm.net
[目的] 探究绿原酸(CGA) 对高游离脂肪酸(FFA) 处理的犊牛肝细胞胆固醇和胆汁酸代谢的影响.[
方法] 采用两步胶原酶灌注法分离犊牛原代肝细胞, 利用免疫荧光鉴定细胞后将其分为4 组 …