It is becoming clearer how neurobiological mechanisms generate 'liking'and
'wanting'components of food reward. Mesocorticolimbic mechanisms that enhance …

The specific metabolic contribution of consuming different energy-yielding macronutrients
(namely, carbohydrates, protein and lipids) to obesity is a matter of active debate. In this …

Under normal conditions, food intake and energy expenditure are balanced by a
homeostatic system that maintains stability of body fat content over time. However, this …

Food is a potent natural reward and food intake is a complex process. Reward and
gratification associated with food consumption leads to dopamine (DA) production, which in …

Hypothalamic-pituitary-gonadal (HPG) axis function fundamentally affects the physiology of
eating. We review sex differences in the physiological and pathophysiological controls of …

The objective of this non-systematic review of the literature is to highlight some of the neural
systems and pathways that are affected by the various intake-promoting aspects of the …

Post-ingestive nutrient signals to the brain regulate eating behaviour in rodents, and
impaired responses to these signals have been associated with pathological feeding …

Abstract Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1
(NAG-1), is associated with a large number of biological processes and diseases, including …

Experiments in animals suggest that the neuropeptide oxytocin acts as an anorexigenic
signal in the central nervous control of food intake. In humans, however, research has …

In recent years, we've developed a much better grasp of the biological and other factors
associated with the development of obesity. Reflecting our evolving understanding of …