In higher eukaryotes, enhancers determine the activation of developmental gene
transcription in specific cell types and stages of embryogenesis. Enhancers transform the …

The rice and wheat agricultural system is the primary source of food for billions across the
world. However, the productivity and long‐term sustainability of rice and wheat are …

The Hedgehog (Hh) signaling pathway is pervasively involved in human malignancies,
making it an effective target for cancer treatment for decades. In addition to its direct role in …

Clustered regularly interspaced short palindromic repeats (CRISPR)—CRISPR associated
protein (Cas) technology is an effective tool for site-specific genome editing, used to …

A morphogen is a signaling molecule that induces specific cellular responses depending on
its local concentration. The concept of morphogenic gradients has been a central paradigm …

This study investigated photobiomodulation (PBM) effects in Sonic hedgehog (Shh)
signaling as a potential approach to taste preservation and regeneration. Primary taste cell …

Much of our current understanding of rare human diseases is driven by coding genetic
variants. However, non-coding genetic variants play a pivotal role in numerous rare human …

Schwann cells play a critical role after peripheral nerve injury by clearing myelin debris,
forming axon-guiding bands of Büngner, and remyelinating regenerating axons. Schwann …

Abstract Ellis–van Creveld syndrome (EvC) is an autosomal recessive genetic disorder
involving pathogenic variants of EVC and EVC2 genes and classified as a ciliopathy. The …

Mapping accessible chromatin across time scales can give insights into its dynamic nature,
for example during cellular differentiation and tissue or organism development. Analysis of …