NK cells sit at the crossroads of innate and adaptive immunity and help coordinate tumor
immunosurveillance and the immune response against pathogens. Balancing signals to NK …

Natural killer (NK) cells are CD56+ CD3− large granular lymphocytes that constitute a key
component of the human innate immune response. In addition to their potent cytolytic …

Human cytomegalovirus, a chief pathogen in immunocompromised people, can persist in a
healthy immunocompetent host throughout life without being eliminated by the immune …

Inhibitory receptors for MHC class I molecules increase the threshold of lymphocyte
activation. Natural Killer (NK) cells express a large number of such inhibitory receptors …

Natural killer (NK) cells have a crucial role in combating infections and cancers and their
surface receptors can directly recognize and respond to damaged, transformed or non-self …

Regulatory T cells (Treg) are key players in the maintenance of peripheral tolerance. As a
result of suppressive effects on CD4+ and CD8+ effector T cells, Treg control the adaptive …

One of the most complicated organs of higher organisms is the immune system. The function
of the immune system is to fight off pathogenic organisms that enter and grow within the host …

Natural killer (NK) cells are sentinel components of the innate response to pathogens, but
the cell types, pathogen recognition receptors, and cytokines required for their activation in …

INTRODUCTION: Ewing sarcoma (EWS) is a malignant bone-associated sarcoma, with poor
prognosis in case of metastasis or relapse. To explore the feasibility of natural killer (NK) cell …

Natural killer (NK) cells are crucial for immune responses to viral infections. CD160 is an
important NK cell activating receptor, with unknown function in HIV infection. Here, we found …